Pluristem to Conduct Phase III Trial of PLX-PAD Following Hip Fracture Surgery

By Julie A. Vetalice

Pluristem Therapeutics intends to conduct a U.S./EU Phase III trial assessing use of PLX-PAD (PLacental eXpanded) cells to support recovery following surgery for femoral neck fracture.

The study design builds upon positive data from the Phase II trial which showed that PLX-PAD cells induced significant muscle regeneration following total hip replacement. Compared to placebo, patients treated with PLX-PAD at the time of surgery showed a 500% improvement in muscle force and a 300% improvement in muscle volume at 6 months.

Earlier results from the Phase I/II study were announced in 1Q15.

Sources: Plurstem Therapeutics, Inc.; ORTHOWORLD Inc.

Product Labels: PRP/Cell-Based/Osteoinductive Materials, Trauma Hip

Tags: Trial/Study