MicroGen Diagnostics introduced OrthoKEY, a diagnostic tool that integrates synovial fluid analyses for biomarkers and white blood cell count with other parameters needed to make a diagnosis of periprosthetic joint infection (PJI).
This evidence-based, algorithmic approach provides clinicians with the likelihood of infection, with additional guidance on antimicrobial treatment with analysis of 17 antimicrobial resistance genes. OrthoKEY offers comprehensive, actionable diagnostic information in just 1-2 days.
OrthoKEY technologies have proven effective in detecting and managing infections involving polymicrobial communities, viable but nonculturable (VBNC) bacteria, anaerobes and atypical organisms, all of which can contribute to PJI even as they evade culture. MicroGenDX technology can identify the infective organism(s) in up to 90% of culture-negative infections, based on numerous studies.
Two new products are available: OrthoKEY Clinic for aspiration samples, and OrthoKEY Surgery. The latter includes the CaptiGen® flat swab for enhanced absorption of microbial DNA, biofilm retrieval and nucleic acid extraction.