Top-line results from the SOLARIO study (Short or Long Antibiotic Regimes in Orthopaedics) show that patients with orthopedic infections, who were surgically treated with antibiotic-eluting bone substitute materials such as BONESUPPORT’s CERAMENT G and CERAMENT V, achieved equally good infection prevention with a short systemic antibiotic course of no more than seven days, compared to the previous standard treatment that extends over at least four weeks. The group that received the shorter antibiotic treatment exhibited significantly reduced side effects compared to standard treatment.
SOLARIO is a randomized controlled multicenter trial involving 500 adult patients with orthopedic infections. Patients were surgically treated with antibiotic-eluting bone substitute materials and received additional intravenous and/or oral systemic antibiotics for either at least four weeks (standard treatment) or a maximum of seven days (intervention treatment).
The aim of the study is to demonstrate that antibiotic-eluting bone substitute materials enable a shortened duration of systemic antibiotic therapy, which could offer significant benefits for both patients and society. These benefits include shorter treatment times, reduced antibiotic costs, fewer side effects, better patient adherence, improved antibiotic stewardship and a reduced risk of antibiotic resistance.
Top-line results from the SOLARIO study (Short or Long Antibiotic Regimes in Orthopaedics) show that patients with orthopedic infections, who were surgically treated with antibiotic-eluting bone substitute materials such as BONESUPPORT's CERAMENT G and CERAMENT V, achieved equally good infection prevention with a short systemic antibiotic course...
Top-line results from the SOLARIO study (Short or Long Antibiotic Regimes in Orthopaedics) show that patients with orthopedic infections, who were surgically treated with antibiotic-eluting bone substitute materials such as BONESUPPORT’s CERAMENT G and CERAMENT V, achieved equally good infection prevention with a short systemic antibiotic course of no more than seven days, compared to the previous standard treatment that extends over at least four weeks. The group that received the shorter antibiotic treatment exhibited significantly reduced side effects compared to standard treatment.
SOLARIO is a randomized controlled multicenter trial involving 500 adult patients with orthopedic infections. Patients were surgically treated with antibiotic-eluting bone substitute materials and received additional intravenous and/or oral systemic antibiotics for either at least four weeks (standard treatment) or a maximum of seven days (intervention treatment).
The aim of the study is to demonstrate that antibiotic-eluting bone substitute materials enable a shortened duration of systemic antibiotic therapy, which could offer significant benefits for both patients and society. These benefits include shorter treatment times, reduced antibiotic costs, fewer side effects, better patient adherence, improved antibiotic stewardship and a reduced risk of antibiotic resistance.
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