Acuitive Technologies received FDA 510(k) clearance to market CITREPORE, a synthetic bioactive bone void filler, using their patented CITREGEN biomaterial technology. Following placement in a bony void, CITREPORE is resorbed predictably and replaced by the patient’s bone, providing Citrate to guide the healing process metabolically.
Highlights of the CITREPORE Synthetic Bone Void Filler include:
Greater than 80% porosity with exceptional ability to absorb and retain fluids such as saline, autogenous blood and bone marrow aspirate
Resorbs predictably while mitigating chronic inflammation
Is both Osteoconductive and Bioactive
It is offered in an array of pre-formed shapes and sizes and can be cut or morselized by pulling it apart by hand or with cutting instruments routinely available in the OR
It is indicated for voids or gaps in the skeletal system (extremities and pelvis) that are not intrinsic to the stability of the bony structure
Richard Tran, PhD, VP of Research at Acuitive Technologies, points to recent research from the University of Galway and Colorado State University, finding that “Citrate, a critical intermediate in the Krebs cycle, is highly concentrated in native bone and is closely associated with bone metabolism and formation. In response to citrate, human stem cells increase genetic signaling for metabolism, osteoinduction, osteoconduction, and extracellular matrix production.”
Acuitive Technologies received FDA 510(k) clearance to market CITREPORE, a synthetic bioactive bone void filler, using their patented CITREGEN biomaterial technology. Following placement in a bony void, CITREPORE is resorbed predictably and replaced by the patient’s bone, providing Citrate to guide the healing process metabolically.
Highlights...
Acuitive Technologies received FDA 510(k) clearance to market CITREPORE, a synthetic bioactive bone void filler, using their patented CITREGEN biomaterial technology. Following placement in a bony void, CITREPORE is resorbed predictably and replaced by the patient’s bone, providing Citrate to guide the healing process metabolically.
Highlights of the CITREPORE Synthetic Bone Void Filler include:
Greater than 80% porosity with exceptional ability to absorb and retain fluids such as saline, autogenous blood and bone marrow aspirate
Resorbs predictably while mitigating chronic inflammation
Is both Osteoconductive and Bioactive
It is offered in an array of pre-formed shapes and sizes and can be cut or morselized by pulling it apart by hand or with cutting instruments routinely available in the OR
It is indicated for voids or gaps in the skeletal system (extremities and pelvis) that are not intrinsic to the stability of the bony structure
Richard Tran, PhD, VP of Research at Acuitive Technologies, points to recent research from the University of Galway and Colorado State University, finding that “Citrate, a critical intermediate in the Krebs cycle, is highly concentrated in native bone and is closely associated with bone metabolism and formation. In response to citrate, human stem cells increase genetic signaling for metabolism, osteoinduction, osteoconduction, and extracellular matrix production.”
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