Newly-published results from a 5-year study of Aesculap Implant Systems’ activL® lumbar artificial disc indicate that, in select patients, lumbar total disc replacement (LTDR) is more effective than fusion at slowing the adjacent segment degenerative cascade.
Post-hoc analysis used all available radiographic data from the activL Investigative Device Exemption study, examining rates of adjacent-level degeneration (ALD) after LTDR with either activL or Centinel Spine’s ProDisc-L as control. Authors found a 9.7% incidence rate of radiographic adjacent level deterioration at five years vs. previous reports of deterioration at levels above fusion (28.6%) and a 2.29% rate of clinically-significant ALD that resulted in additional surgery.
activL and ProDisc-L are the only lumbar artificial discs approved in the U.S. that have been evaluated for ALD rates. (activL was approved in 2015.)
Full text of the article, “Progression of Adjacent-level Degeneration after Lumbar Total Disc Replacement: Results of a Post-hoc Analysis of Patients with Available Radiographs from a Prospective Study with 5-year Follow-up,” is available from Spine.
Newly-published results from a 5-year study of Aesculap Implant Systems' activL® lumbar artificial disc indicate that, in select patients, lumbar total disc replacement (LTDR) is more effective than fusion at slowing the adjacent segment degenerative cascade.
Post-hoc analysis used all available radiographic data from the activL Investigative...
Newly-published results from a 5-year study of Aesculap Implant Systems’ activL® lumbar artificial disc indicate that, in select patients, lumbar total disc replacement (LTDR) is more effective than fusion at slowing the adjacent segment degenerative cascade.
Post-hoc analysis used all available radiographic data from the activL Investigative Device Exemption study, examining rates of adjacent-level degeneration (ALD) after LTDR with either activL or Centinel Spine’s ProDisc-L as control. Authors found a 9.7% incidence rate of radiographic adjacent level deterioration at five years vs. previous reports of deterioration at levels above fusion (28.6%) and a 2.29% rate of clinically-significant ALD that resulted in additional surgery.
activL and ProDisc-L are the only lumbar artificial discs approved in the U.S. that have been evaluated for ALD rates. (activL was approved in 2015.)
Full text of the article, “Progression of Adjacent-level Degeneration after Lumbar Total Disc Replacement: Results of a Post-hoc Analysis of Patients with Available Radiographs from a Prospective Study with 5-year Follow-up,” is available from Spine.
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