Trial/Study

October 1, 2021

Clinical Study: Treace Medical Mini3D Lapiplasty

Clinical Study: Treace Medical Mini3D Lapiplasty
The first patient was treated in the Mini3D Lapiplasty clinical study, which will evaluate outcomes using Lapiplasty Mini-Incision.
September 30, 2021

Study Results: Conformis iTotal CR Knee

Study Results: Conformis iTotal CR Knee
Review of 540 procedures revealed 98.5% implant survivorship and 89.0% patient satisfaction for the patient-specific iTotal CR device.
September 22, 2021

Clinical Trial: Medtronic Pediatric Spinal Tether

Clinical Trial: Medtronic Pediatric Spinal Tether
The trial will evaluate the Braive growth modulation system to treat progressive Adolescent Idiopathic Scoliosis.
September 8, 2021

Study Update: OssDsign Synthetic Bone Graft

Study Update: OssDsign Synthetic Bone Graft
The first patient has been treated in a study to investigate OssDsign Catalyst in patients undergoing spinal fusion.
September 7, 2021

Study Results: PainTEQ LinQ in SI Joint Dysfunction

Study Results: PainTEQ LinQ in SI Joint Dysfunction
Results show that posterior SI joint fusion with LinQ has the potential to rescue patients with inadequate relief from previous therapies.
August 31, 2021

AAOS Reports Trends, Outcomes from Joint Registries

AAOS Reports Trends, Outcomes from Joint Registries
Clinical data reports from the American Joint Replacement and Shoulder & Elbow Registry reports offer actionable information on patient care.
August 31, 2021

Study: Centinel Spine prodisc L Effectiveness

Study: Centinel Spine prodisc L Effectiveness
The study expands the evidence of the prodisc L disc replacement with results up to 21 years across a large patient cohort.
July 28, 2021

Carlsmed Partners to Study aprevo Spinal Device

Carlsmed Partners to Study aprevo Spinal Device
The International Spine Study Group Foundation will help collect data on surgical treatment with the personalized interbody device.
July 15, 2021

Active Implants NUsurface Meniscus Study Results

Active Implants NUsurface Meniscus Study Results
The NUsurface Implant is the first artificial meniscus to be marketed in Europe and is currently under review by FDA.
June 30, 2021

Histogen Initiates Knee Cartilage Regeneration Trial

Histogen Initiates Knee Cartilage Regeneration Trial
Histogen's human extracellular matri is intended for regenerating hyaline cartilage for the treatment of articular cartilage defects.
June 8, 2021

Study Results: Spinal Elements Luna XD Multi-Expandable Interbody

Study Results: Spinal Elements Luna XD Multi-Expandable Interbody
Retrospective analysis of 69 consecutive patients over a 2-year period demonstrated statistically significant improvement in leg/back pain, disability index, etc.
June 4, 2021

Histogen Development and Pipeline Update

Histogen Development and Pipeline Update
The company plans to focus its regenerative medicine platform on orthopedic product candidates to repair the knee and spinal disc.
May 10, 2021

Puregraft Fat Used to Treat Knee Osteoarthritis

Puregraft Fat Used to Treat Knee Osteoarthritis
Studies indicate that Puregraft fat grafting significantly improved function and symptom relief at 3 and 6 months in patients with knee OA.
April 27, 2021

DiscGenics Study Updates: Injectable Discogenic Cell Therapy

DiscGenics Study Updates: Injectable Discogenic Cell Therapy
The company has completed enrollment in its Japanese safety study of allogeneic, injectable discogenic cell therapy for lumbar disc degeneration.
February 17, 2021

Signature Cord Prime Phase 1 Study for Knee OA

Signature Cord Prime Phase 1 Study for Knee OA
FDA approved an IND Application to study Signature Cord Prime in patients with symptomatic osteoarthritis of the knee.
February 16, 2021

Study Results: BandGrip Skin Closure Device

Study Results: BandGrip Skin Closure Device
BandGrip is reportedly more than five times faster in closing orthopedic incisions compared to traditional sutures.
February 1, 2021

Study Results for X-Bolt Sliding Hip Screw

Study Results for X-Bolt Sliding Hip Screw
The WHITE4 study compared the company's flagship X-Bolt XHS device vs. the gold standard Sliding Hip Screw treatment.
February 1, 2021

Synergy Disc Enrolls First Patient in Clinical Trial

Synergy Disc Enrolls First Patient in Clinical Trial
The multicenter study will examine efficacy of the Synergy Disc vs. anterior cervical discectomy and fusion in patients with degenerative disc disease.
January 20, 2021

FDA Clinical Hold for Histogen Trial in Knee Regeneration

FDA Clinical Hold for Histogen Trial in Knee Regeneration
FDA verbally notified the company of additional questions in the application for the planned Phase I/II trial of HST-003 combined with microfracture.
January 12, 2021

Bone Therapeutics Kicks Off ALLOB Tibial Fracture Study

Bone Therapeutics Kicks Off ALLOB Tibial Fracture Study
ALLOB will be applied by a single injection up to 4 days post-reduction surgery in patients with fresh tibial fractures at risk for delayed or non-union.
January 6, 2021

Study Validates NuVasive X360 Approach

Study Validates NuVasive X360 Approach
The single position circumferential fusion was found to improve operative efficiency and reduce complications vs. traditional circumferential fusion.
December 22, 2020

Study Update: Bone Therapeutics’ Phase III Knee Trial

Study Update: Bone Therapeutics’ Phase III Knee Trial
The company has completed recruitment and treated all patients in its Phase III study with the viscosupplement, JTA-004, in patients with knee osteoarthritis.
December 18, 2020

Aurora Spine Plans Study of ZIP Interspinous Fixation

Aurora Spine Plans Study of ZIP Interspinous Fixation
In 1Q21, Aurora will begin a multicenter study of its ZIP Interspinous Fixation device for the treatment of degenerative disc disease.
December 16, 2020

Study Results: Episealer Implant Survival Rate

Study Results: Episealer Implant Survival Rate
Postmarket surveillance data for the Episealer Knee show a cumulative survival rate of >96% over 7 years.
November 17, 2020

AlloSource Completes ProChondrix Study Milestone

AlloSource Completes ProChondrix Study Milestone
First patients completed 12-month follow-up in its prospective, multi-center study of ProChondrix CR to repair knee articular cartilage defects.
November 17, 2020

Smith+Nephew 2-Year NOVOSTITCH Study

Smith+Nephew 2-Year NOVOSTITCH Study
NOVOSTITCH Meniscal Repair Systems achieved 82.6% success rate for difficult to repair horizontal cleavage tears at two year follow-up.
November 6, 2020

Preliminary Results from Zimmer Biomet mymobility Study

Preliminary Results from Zimmer Biomet mymobility Study
Early results of the mymobility remote care management platform on Apple Watch and iPhone demonstrate significant reductions in in-person physical therapy.
October 14, 2020

ALLOB Shows 90% Fusion Rate at 2 Years in Phase IIa Study

ALLOB Shows 90% Fusion Rate at 2 Years in Phase IIa Study
90% of patients show bone fusion as well as strong clinical improvements in function and pain at 24 months follow-up with a good product safety profile.
October 6, 2020

Spineart Conducts Ti-LIFE Animal Study

Spineart Conducts Ti-LIFE Animal Study
Ti-LIFE Technology is an enhanced algorithm for additive manufacturing of titanium cages resulting in structures with a bone-like matrix.
October 5, 2020

Spineology Duo Postmarket Study Completes Enrollment

Spineology Duo Postmarket Study Completes Enrollment
The Duo spinal system has demonstrated reduced operative times, shorter hospital stays and improved clinical outcomes vs. traditional lateral surgery.
September 8, 2020

Episurf Medical Episealer Knee Study Updates

Episurf Medical Episealer Knee Study Updates
Episurf marked the first surgery in the IDE study in Europe, and positive study results with up to 7 year follow-up in patients receiving an Episealer Knee.
August 6, 2020

Spineart Gains IDE Approval for BAGUERA C Trial

Spineart Gains IDE Approval for BAGUERA C Trial
The single-level trial will compare the BAGUERA C Cervical Disc Prothesis to another FDA approved arthroplasty device at up to 30 U.S. sites.
July 17, 2020

Empirical Spine Completes Enrollment in LimiFlex Trial

Empirical Spine Completes Enrollment in LimiFlex Trial
The U.S. IDE trial is studying use of LimiFlex with decompression for patients suffering from degenerative spondylolisthesis with lumbar spinal stenosis.
June 15, 2020

Providence Medical Enrolls in FUSE IDE Study

Providence Medical Enrolls in FUSE IDE Study
FUSE is designed to demonstrate superiority of Circumferential Cervical Fusion vs. traditional ACDF in patients at high risk for nonunion or revisions.
June 15, 2020

BONESUPPORT Completes Trial Enrollment

BONESUPPORT Completes Trial Enrollment
Enrollment of the FORTIFY study on CERAMENT G has been completed, with 198 subjects enrolled. BONESUPPORT expects to submit a PMA application in late 2021.
June 9, 2020

Relievant 5-Year Study Data for Intracept Procedure

Relievant 5-Year Study Data for Intracept Procedure
Relievant announces publication of 5-year data demonstrating long term clinical benefits of the Intracept procedure in chronic low back pain patients.
May 26, 2020

Orteq Shares 5-Year Study Data for Actifit Meniscal Scaffold

Orteq Shares 5-Year Study Data for Actifit Meniscal Scaffold
The synthetic biodegradable polymer is designed to preserve the knee joint and promote new tissue growth in damaged areas of an irreparable meniscus.
May 15, 2020

Histogen Publishes Preclinical Data on Spinal Disc Repair

Histogen Publishes Preclinical Data on Spinal Disc Repair
The company's cell conditioned media has been shown to stimulate stem cells in vivo, possibly leading to the repair of the intravertebral disc matrix.
April 29, 2020

Bone Therapeutics Secures EUR 11.0 Million Financing

Bone Therapeutics Secures EUR 11.0 Million Financing
Funds will support studies of ALLOB allogeneic cell therapy to treat difficult tibial fractures and JTA-004 protein to treat for osteoarthritic knee pain.
April 7, 2020

InGeneron Cell Therapy in Rotator Cuff Repair – Study Results

InGeneron Cell Therapy in Rotator Cuff Repair – Study Results
InGeneron announces favorable study results using regenerative autologous adipose-derived cells that are prepared with the Transpose® RT System for treatment of partial-thickness rotator cuff tears.
March 31, 2020

Episealer Knee Preliminary Study Results

Episealer Knee Preliminary Study Results
Preliminary results from a study of Episurf Medical's Episealer® Knee implant show good patient satisfaction and good knee function.
March 12, 2020

Episurf Medical Reports Episealer Knee Study Results

Episurf Medical Reports Episealer Knee Study Results
Results from a clinical study of Episurf Medical's Episealer® Knee show good implant safety and significantly improved patient-reported outcome scores.
March 12, 2020

Ortho Regenerative Technologies Results from Rotator Cuff Tear Repair Study

Ortho Regenerative Technologies Results from Rotator Cuff Tear Repair Study
Ortho Regenerative Technologies confirmed the safety profile of ORTHO-R biopolymer as well as statistical significance over standard-of-care following completion of a pivotal preclinical study in rotator cuff tear repair.
March 12, 2020

Arthrosurface OVO with Inlay Glenoid Total Shoulder Study Update

Arthrosurface OVO with Inlay Glenoid Total Shoulder Study Update
Study results indicate that use of Arthrosurface's OVO® with Inlay Glenoid Shoulder Arthroplasty System to treat glenohumeral OA yielded improved clinical outcomes, no reoperations or radiographic loosening and a high rate of return to activity.
March 10, 2020

NuVasive Attrax Putty Study Results

NuVasive Attrax Putty Study Results
Study results support the use of NuVasive's Attrax® Putty as a standalone bone graft substitute for autograft in instrumented thoracolumbar posterolateral lumbar fusion.
February 26, 2020

RTI Surgical SImmetry System Interim Study Results

RTI Surgical SImmetry System Interim Study Results
RTI Surgical's SImmetry® sacroiliac fusion system yielded evidence of fusion in 98% of treated joints, per interim study results.
February 11, 2020

INSPAN Reports Study Results from Inspan Interspinous Fixation Device

INSPAN Reports Study Results from Inspan Interspinous Fixation Device
INSPAN announced successful results from a long-term follow-up clinical study of outpatient L4-L5 lumbar interspinous fixation for degenerative spinal stenosis using the Inspan® ScrewLES™ Fusion interspinous fixation device.
February 10, 2020

Tenon Medical’s Catamaran SI Fixation Study Results

Studies indicate that Tenon Medical's Catamaran™ Sacroiliac Joint Fixation System demonstrated an over 85% reduction in SIJ pain at six weeks, with radiographic evidence of solid continuous bridging bone across the treated joint at six months.
December 18, 2019

Episurf Medical EU Clinical Trial Updates for Episealer

Episurf Medical EU Clinical Trial Updates for Episealer
Episurf Medical's Episealer® knee implant system continues to deliver excellent results in multiple ongoing clinical trials.
December 17, 2019

Study Results: RTI Surgical’s TETRAfuse 3D PEKK Technology

Studies show that RTI Surgical's TETRAfuse® PEKK implants demonstrated bone ingrowth, no radiographic interference, no fibrotic tissue membrane formation, a significant increase in bony apposition over time and a significantly higher push-out strength vs. standard PEEK.
December 9, 2019

CartiHeal Announces Positive Interim Results of Agili-C IDE Study

CartiHeal Announces Positive Interim Results of Agili-C IDE Study
CartiHeal announced that per the results of an interim analysis of the IDE study of Agili-C™ in the treatment of cartilage lesions, trial enrollment will stop at 250 subjects.
December 5, 2019

Empirical Spine Completes Portion of Enrollment for LimiFlex Clinical Trial

Empirical Spine completed enrollment in the investigational arm of its U.S. IDE trial of the LimiFlex Paraspinous Tension Band with decompression to treat degenerative spondylolisthesis with lumbar spinal stenosis.
November 14, 2019

Personalized Stem Cells Clinical Trial Update

Personalized Stem Cells treated the first patients in an FDA-approved clinical trial for stem cell treatment of knee osteoarthritis.
November 4, 2019

Spineology U.S. Fusion Trial 24-Month Outcomes Data

Spineology U.S. Fusion Trial 24-Month Outcomes Data
Two-year outcomes from Spineology's SCOUT trial of the OptiMesh® device revealed substantial improvements in low back pain and function scores at 6, 12 and 24 months. 
October 9, 2019

Arthrosurface OVO with Inlay Glenoid Total Shoulder Study Update

Results of a study of Arthrosurface's OVO® with Inlay Glenoid Shoulder Arthroplasty System demonstrated excellent clinical benefits, including pain relief and increased range of motion in patients with glenohumeral arthritis.
September 27, 2019

DiscGenics IDCT Study Update

Preclinical study results demonstrated that intradiscal injection of Discogenic Cells, the active ingredient in DiscGenics' IDCT allogeneic cell therapy, may be a viable treatment for degenerative disc disease.
September 26, 2019

SI-BONE 5-Year iFuse Study Results

SI-BONE reports that 5-year follow-up from studies of the iFuse implant for SI joint fusion showed excellent durability of clinical responses and positive radiographic outcomes.
September 26, 2019

4WEB Medical Completes Cell Differentiation and Gene Expression Study

4WEB Medical completed Phase I in vitro testing to demonstrate that surface roughness on its 3D-printed truss implants stimulates a superior osteogenic response vs. smooth titanium and PEEK.
September 25, 2019

Stryker Announces SAKOS Pivotal Trial Results for SpineJack

Results from the SAKOS pivotal trial of Stryker's SpineJack® implantable fracture reduction system successfully demonstrated non-inferiority to balloon kyphoplasty (BKP), with an excellent risk/benefit profile for up to 12 months.
September 25, 2019

Benvenue Medical Releases MIS TLIF Clinical Data on Luna Device

Clinical studies of Benvenue Medical's Luna interbody fusion device in minimally invasive Transforaminal Lumbar Interbody Fusion (TLIF) showed improved patient outcomes and decreased back and leg pain at 12 months post-op.
September 13, 2019

X-BOLT Hip Fixation Shows 0.8% Reoperation Rate in Study

Preliminary study results indicate that X-BOLT Orthopaedics' X-BOLT device for hip fracture repair demonstrated a cut-out rate of 0.8% in a population of 476 patients, and performed as well as a hip sliding screw in measures such as quality of life, mortality, revision, etc.
September 3, 2019

Kuros to Begin Fibrin-PTH Clinical Trial in Spinal Fusion

Kuros Biosciences gained FDA approval for its IND application to initiate a Phase IIA clinical trial evaluating Fibrin-PTH orthobiologic in single-level TLIF to treat degenerative disc disease, with autograft as comparator.
August 16, 2019

Aesculap activL Lumbar Disc: 5-Year Study Results

At five-year follow-up, Aesculap Implant Systems' activL® lumbar disc was found to more effectively preserve range of motion vs. first-generation lumbar total disc replacement devices to treat degenerative disc disease.
August 9, 2019

Kinamed CarboJet Bone Preparation System Study Results

Studies demonstrate that use of Kinamed's CarboJet® CO2 Bone Preparation System yields increased bone cement penetration in total knee arthroplasty, even without a tourniquet.
July 24, 2019

Miach Orthopaedics BEAR Implant ACL Repair Study

Miach Orthopaedics announced study results showing that torn anterior cruciate ligaments (ACLs) treated with the Bridge-Enhanced® ACL Repair (BEAR®) implant were similar to the native ACL at one year.
July 19, 2019

Centinel Spine Announces prodisc C Clinical Trials

Centinel Spine received Investigational Device Exemption approval to initiate a two-level clinical trial with prodisc® C Vivo and prodisc C SK anterior cervical total discs.
July 18, 2019

ExactechGPS Study Results: Knee and Shoulder Replacement

ExactechGPS Study Results: Knee and Shoulder Replacement
Study results indicate that use of Exactech's ExactechGPS® computer-assisted technology yielded an improved surgical experience in knee and shoulder joint reconstruction.
July 12, 2019

Smith & Nephew NOVOSTITCH Study Results

Study results indicate that Smith & Nephew's NOVOSTITCH knee meniscal repair technology delivered a 0% re-operation rate and 100% meniscal healing at 6 months.
June 12, 2019

CartiHeal Enrolls 200th Patient in Agili-C Study

CartiHeal, developer of the Agili-C implant to treat cartilage and osteochondral defects, enrolled the 200th patient in the Agili-C IDE pivotal clinical study.
May 30, 2019

CartiHeal’s Agili-C Implant In-vitro Study Results

CartiHeal announced a study demonstrating that the Agili-C implant may enhance osteogenic differentiation of human bone marrow-derived mesenchymal stem cells.
May 28, 2019

Globus Medical ExcelsiusGPS Shows 99% Screw Placement Success

Globus Medical ExcelsiusGPS Shows 99% Screw Placement Success
Globus Medical's ExcelsiusGPS® robotic navigation system demonstrated a 99% success rate in pedicle screw placement in the first 100 cases at a single center.
May 22, 2019

Smith & Nephew OXINIUM Technology: $296MM in Potential U.S. Health System Savings

Data collected using the Comprehensive Care for Joint Replacement model suggests that if Smith & Nephew's OXINIUM bearing surface was used in all U.S. primary hip procedures in 2020, it could yield ~$296MM in savings to the nation's health system.
May 17, 2019

Treace Medical: Lapiplasty 3D Bunion Correction Multicenter Study Results

Results from a retrospective, multicenter study with Treace Medical's Lapiplasty® 3D Bunion Correction procedure revealed a 96.8% maintenance of 3-plane correction at 13.5-month follow-up with an early weight-bearing protocol.
May 2, 2019

Centinel Spine Reports New prodisc C Study Results

Centinel Spine announced results from a single-center study that suggest strong support of the safety of the prodisc® C cervical artificial disc.
April 23, 2019

NuVasive Cohere Porous PEEK Comparative Study Results

NuVasive's Cohere® Porous PEEK interbody demonstrated clear benefits in promoting improved early outcomes in ACDF procedures when compared to both structural allograft and smooth PEEK.
April 18, 2019

Shoulder Innovations Announces Long Term Data for Inset Glenoid

Shoulder Innovations' InSet Glenoid demonstrated long-term efficacy and safety in total shoulder replacement to reconstruct deficient, arthritic glenoid bone.
April 11, 2019

BONESUPPORT: Study Affirms Cerament Remodels into Human Bone

Retrospective review of 163 patients at one-year follow-up revealed clinical evidence of BONESUPPORT's CERAMENT® bone void filler remodeling into bone in humans.
April 4, 2019

Orthofix M6-C Artificial Cervical Disc Study: Full 2-Year Data

Full 2-year outcomes from a U.S. IDE study of Orthofix Medical's M6-C artificial cervical disc demonstrated that disc replacement with the device is not inferior to treatment with ACDF.
March 28, 2019

FzioMed Enrolls 50th Patient in Oxiplex Study

FzioMed reached a milestone of 1/3 patient enrollment in a clinical study of Oxiplex® gel for reduction of pain following partial discectomy.
March 21, 2019

AlloSource Enrolls in ProChondrix CR Study

AlloSource enrolled the first patient in a study to evaluate the effectiveness of ProChondrix CR® fresh cryopreserved osteochondral allograft, when used on cartilage defects in the knee.
March 14, 2019

Smith & Nephew POLAR3 Total Hip: Results from National Joint Registry

Smith & Nephew's POLAR3 total hip system demonstrated excellent survivorship and significantly higher patient satisfaction vs. other cementless stems in National Joint Registry in the U.K.
March 13, 2019

CyMedica Orthopedics: e-vive Clinical Trial Results

CyMedica Orthopedics' e-vive app-driven muscle strengthening device demonstrated statistically significant and positive results in a clinical trial evaluating the recovery of total knee replacement patients.
March 12, 2019

OrthoSensor Shares New VERASENSE Clinical Highlights

New clinical data suggest that use of OrthoSensor's VERASENSE sensor-assisted technology for total knee replacement helps address tissue balance and improve patient outcomes.
March 12, 2019

Stryker Mako Total Knee: Clinical Studies Demonstrate Early Functional Recovery

Clinical studies demonstrated that Stryker's Mako Total Knee was associated with less pain and need for opiates, shorter hospital stays, improved flexion and soft tissue protection vs. manual techniques.
March 12, 2019

Miach Orthopaedics 2-Year Study Results on ACL Repair

Results from a feasability study indicate that use of the Bridge-Enhanced® ACL Repair (BEAR®) procedure from Miach Orthopaedics resulted in similar clinical, functional and patient-reported outcomes as autograft ACL reconstruction at 24 months.
March 7, 2019

CartiHeal Study Enrolls 150th Patient

CartiHeal announced treatment of the 150th patient in the IDE clinical study of Agili-C for knee cartilage repair.
March 4, 2019

Aesculap Biologics Announces NOVOCART 3D Trial Enrollment Milestone

Aesculap Biologics achieved 50% enrollment in its Phase III clinical trial of NOVOCART® 3D, an autologous chondrocyte transplantation system to treat articular cartilage defects in the knee.
February 19, 2019

Seikagaku and Ono Announce Positive Study Results

Seikagaku and Ono Pharmaceutical obtained positive topline results from a Phase III confirmatory study of an HA/NSAID formulation in the treatment of knee OA.
February 5, 2019

FH Orthopedics: LP-ESP Disc Replacement Study Update

Study results indicate that FH Orthopedics' LP-ESP® Lumbar Prosthesis demonstrated excellent midterm follow-up results in total disc replacement at five years.
January 28, 2019

Aesculap Implant Systems PlasmaporeXP Surface Enhancement Study

Studies of Aesculap Implant Systems' Plasmapore®XP Surface Enhancement indicate that early bone-forming activity was upregulated in osteoblast-like cells that attached to the PlasmaporeXP. 
January 24, 2019

X-Bolt Orthopaedics: 1,000 Patients Reach One Year in Hip Fracture Trial

X-Bolt Orthopaedics announced that the 1,000th patient has reached one-year follow-up in WHITE4, a randomized controlled trial comparing the X-BOLT® expanding bolt device vs. a sliding hip screw in hip fracture treatment.
January 18, 2019

Flower Orthopedics: FlowerCube Study Results

Study results indicate that use of Flower Orthopedics' FlowerCube implant and instrument system in first metatarsal phalangeal joint fusion at an ASC resulted in a 33% decrease in intraoperative time and $1,300 savings in reimbursement costs, while providing equivalent clinical outcomes.
January 7, 2019

DiscGenics’ IDCT Passes Initial Safety Review in Phase I/II Trial

DiscGenics' injectable disc cell therapy passed an initial planned safety review of its Phase I/II trial for the treatment of mild to moderate degenerative disc disease.
January 3, 2019

Histogenics to Explore Strategic Alternatives for NeoCart Cartilage Treatment

Histogenics plans to evaluate the range of potential strategic alternatives for its NeoCart® cell therapy following FDA's indication that an additional clinical trial would be required before acceptance of a Biologics License Application submission. 
December 19, 2018

Study Results: InSpace Balloon vs. Superior Capsular Reconstruction

Results from cadaveric study of OrthoSpace's InSpace balloon spacer vs. superior capsular reconstruction in the treatment of rotator cuff tears found that InSpace effectively restored the humeral head to a nearly normal position.
November 27, 2018

Safe Orthopaedics Study: Cost Savings with Single-use Instruments

Study results revealed an average 50% cost-per-patient savings with use of Safe Orthopaedics' instruments vs. reusable ones in the treatment of spinal fractures. 
November 26, 2018

aap Implantate Reports Positive LOQTEQ Study Results

In biomechanical study, aap Implantate's LOQTEQ® anatomical fracture plating system displayed better explantation properties than those of the market leader.
November 26, 2018

Vertiflex Study: 85% Reduction in Opiod Use after Treatment with Superion

Results from a randomized, controlled trial of Vertiflex's Superion® Indirect Decompression System showed an 85% decrease in the proportion of patients using opioids, 5 years after treatment for lumbar spinal stenosis. 
November 19, 2018

BONESUPPORT Announces Positive top-line data from the CERTiFy CERAMENT Study

BONESUPPORT announced that the CERTiFy study of CERAMENT bone void filler met its primary endpoint of non-inferiority to autologous iliac bone graft in the treatment of tibia plateau fractures.
November 13, 2018

CartiHeal Enrolls First Agili-C Patient on East Coast

CartiHeal announced successful enrollment of the first patient in the Agili-C IDE pivotal study on the East Coast.
November 13, 2018

Bio2 Gains Approval to Study Vitrium in Interbody Fusion

Bio2 Technologies received FDA approval to enroll subjects in an IDE clinical study of Vitrium bioactive glass as a cervical interbody fusion device.
November 7, 2018

CartiHeal: Positive Study Results for Agili-C Implant

CartiHeal announced a study demonstrating that its Agili-C implant promotes the regenerative capacity of articular cartilage defects in a human cadaveric ex-vivo model.
November 6, 2018

Bone Therapeutics to End Phase III PREOB Study

The Data and Safety Monitoring Board recommended discontinuation of the Phase III hip osteonecrosis study of Bone Therapeutics' PREOB viscosupplement, following interim analysis of results.
October 26, 2018

CartiHeal Reaches 100th Surgery in Agili-C IDE Study

CartiHeal has successfully enrolled and treated the 100th patient in the pivotal IDE study of the Agili-C implant. 
October 23, 2018

Study Results: DJO EMPOWR 3D Knee Reduces Patient Dissatisfaction

Results from a clinical study of DJO's EMPOWR 3D Knee indicate that the technology reduces patient dissatisfaction while improving function and activity levels.
October 23, 2018

Regentis Biomaterials Expands SAGE Trial of GelrinC

Regentis Biomaterials expanded the SAGE clinical trial of GelrinC to 11 U.S. sites. The investigational device is in evaluation to regrow knee cartilage.
October 17, 2018

Bone Therapeutics Reports Results of Viscosupplement Study

Bone Therapeutics' first efficacy study of the JTA-004 viscosupplement to treat knee OA showed that a single injection delivered higher pain reduction vs. a reference product.
October 15, 2018

Zimmer Biomet Launches Study of mymobility Apple Watch App

Zimmer Biomet launched a clinical study of mymobility, an Apple Watch app to support connection between hip and knee replacement patients and their surgical care teams. 
October 1, 2018

Vertos Medical Enrolls in New MOTION Study of MILD Procedure

Vertos Medical enrolled the first patient into MOTION, a new multicenter two-year U.S. study of the mild® outpatient procedure for minimally invasive treatment of lumbar spinal stenosis.
September 28, 2018

Kuros Biosciences: First Procedure in MagnetOS Spinal Fusion Trial

The first patient has been treated in a multicenter study comparing Kuros Bioscience's MagnetOs bone graft substitute vs. autologous bone in spinal fusion.
September 26, 2018

Ethicon’s Skin Closure in Knee Replacement Study

Total knee replacement patients and surgeons reported greater satisfaction with Ethicon's DERMABOND PRINEO Skin Closure System for surgical incisions vs. traditional skin staples.
September 11, 2018

Vertos Medical: Positive Study Results for mild Procedure

Vertos Medical announced that data from a two-year study demonstrates long-term safety and efficacy of mild® lumbar decompression procedure.
September 6, 2018

Histogenics’ Top-Line Results From Phase 3 Trial of NeoCart

Histogenics' Phase III clinical trial of NeoCart® tissue engineered implant did not meet the primary endpoint of a statistically significant improvement in pain and function vs. microfracture in a dual threshold responder analysis at one year.
August 17, 2018

First U.S. Patients Receive Agili-C Implants

CartiHeal announced successful enrollment of the first two U.S. patients in the Agili-C IDE pivotal study.
July 30, 2018

Episurf Hears FDA Feedback on IDE for Episealer Knee

Episurf Medical is entering its next phase on its IDE application to initiate a U.S. clinical study of the Episealer® knee implant. 
July 23, 2018

ReVivo Medical Efficacy Study Results

Results from an efficacy study of ReVivo Medical's spinal fusion technology demonstrated that loadsharing through elastic micro-motion accelerates bone formation and interbody fusion.
July 19, 2018

CoNextions Launches Clinical Trial for Tendon Repair

CoNextions enrolled the first two patients in a clinical trial comparing the CoNextions TR system to suture repair to treat Zone 2 tendon lacerations.
July 16, 2018

Cartiva Synthetic Cartilage Implant Long-Term Clinical Data

Five-year follow-up results demonstrate that Cartiva's Synthetic Cartilage Implant provided long-term durability in pain and functional improvements in the treatment of great toe arthritis.
June 20, 2018

Study Validates NuVasive’s Porous PEEK Cohere

Study results indicate that NuVasive's porous PEEK technology, used in the Cohere® cervical interbody fusion device, presents a clinically viable option to improve osseointegration and fusion.
June 19, 2018

Arthrosurface Trial Results with PF Wave Implant

Five-year midterm clinical study results reconfirmed joint preservation in patellofemoral surgery using Arthrosurface's PF Wave implant.
May 23, 2018

Wenzel Spine Announces Case Study of VariLift-LX System

Wenzel Spine announced publication of a case series detailing endoscopic transforaminal decompression and fusion with the VariLift-LX system.
May 22, 2018

Cerapedics Study Results: i-FACTOR Bone Graft in Lumbar Posterolateral Spine

Study results indicate that Cerapedics' i-FACTOR Peptide Enhanced Bone Graft demonstrated a 50% fusion rate in lumbar posterolateral spine surgery patients vs. 20% fusion rate with allograft.
May 16, 2018

Globus Medical Announces Positive LLIF Study Results

In a study comparing expandable and static LLIF devices, at 2-year follow-up, researchers observed no implant subsidence in patients treated with expandable devices, with 16% subsidence in levels treated with static spacers.
May 1, 2018

X-Bolt Orthopaedics Completes Hip Fracture Trial Enrollment

X-Bolt Orthopaedics completed recruitment of 1,140 patients for WHITE4, a randomized control trial comparing the X-Bolt expanding bolt device vs. a sliding hip screw in hip fracture treatment.
April 30, 2018

Biologica Technologies Presents Update on ProteiOS Growth Factor

Biologica Technologies is debuting initial clinical data from spinal applications using ProteiOS® growth factor. The product, which entered limited U.S. launch in 4Q17, is now available nationwide.
April 27, 2018

DiscGenics Treats First Patient in IDCT Trial

The first patient has been treated in DiscGenics' Phase I/II U.S. clinical trial of IDCT injection to treat degenerative disc disease.
April 25, 2018

Fidia Presents HYMOVIS Viscosupplement Study Data

Studies indicate that Fidia's HYMOVIS® viscosupplement enhanced cartilage volume and thickness in patients suffering from symptomatic knee OA.
April 12, 2018

Augmedics Cadaver Study Results with xvision-spine Navigation

Study results indicate that Augmedics' xvision-spine augmented-reality surgical navigation system was used to place 120 pedicle screws with 96.7% placement accuracy.
April 12, 2018

Spineology U.S. Fusion Trial Interim 12-Month Outcomes Data

Initial outcomes from the SCOUT trial of Spineology's OptiMesh® device revealed statistically significant improvements in low back pain and function scores at 6 and 12 months. 
April 12, 2018

activL Lumbar Disc Study Results: Adjacent-Level Degeneration

Newly-published results from a 5-year study of Aesculap Implant Systems' activL® lumbar disc indicate that, in select patients, lumbar TDR is more effective than fusion at slowing the adjacent segment degenerative cascade.
March 30, 2018

NuVasive Porous PEEK Material Impaction Study Results

Studies demonstrated advantages of NuVasive's Porous PEEK interbody fusion devices vs. titanium-coated PEEK in impaction durability.
March 29, 2018

RTI’s Simmetry Reduces SI Joint Range of Motion

Study results demonstrate that RTI Surgical's Simmetry® Sacroiliac Joint Fusion system provided effective joint fixation, markedly reducing range of motion in the SI joint.
March 23, 2018

Vericel’s MACI Shows Sustained Benefit at Five Years

Study results demonstrated that improvements in pain and function from use of Vericel's MACI vs. microfracture in the treatment of knee cartilage defects were sustained for five years following surgery.
March 14, 2018

Cerapedics Launching IDE Study of P-15L Bone Graft in TLIF

Cerapedics received FDA approval for an IDE clinical trial of P-15L Peptide Enhanced Bone Graft vs. autograft in TLIF to treat degenerative disc disease.
March 8, 2018

Benvenue Medical Luna Interbody Fusion Study Results

Retrospective analysis of Benvenue Medical's Luna® 3D Multi-Expandable Interbody Fusion system indicate that minimally invasive TLIF placement of the device was safe and effective.
March 5, 2018

Orthofix Cervical-Stim Device Shown to Improve Fusion Rates

Studies show that use of pulsed electromagnetic field treatment after ACDF significantly increased the fusion rate vs. control at 6 and 12 months, for participants at risk for pseudoarthrosis.
February 28, 2018

Biomatlante’s MBCP Matrix Selected for Fracture Study

Biomatlante's MBCP+ synthetic bone graft matrix has been selected for comparison to autograft in a 5-year trial in the treatment of long bone nonunions.
February 14, 2018

Orthofix to Study PEMF in Rotator Cuff Repair

Orthofix commenced enrollment in a clinical trial of the RCStim pulsed electromagnetic field device as an adjunct to surgical repair of rotator cuff tears.
January 31, 2018

Bioventus Invests in CartiHeal Study

CartiHeal gained an investment of $2.5MM from Bioventus to support the IDE trial of the Agili-C cartilage regeneration implant.
January 31, 2018

Ceterix Completes Enrollment in NovoStitch Trial

Ceterix Orthopaedics completed enrollment in STITCH, a prospective, non-randomized, multi-center investigation of all-suture-based repair of horizontal meniscal tears.
January 30, 2018

Patient Satisfaction from MicroPort Evolution Knee

Study results suggest that patients who underwent medial-pivot TKA with MicroPort Orthopaedics' Evolution® system scored significantly better on the Forgotten Joint Score vs. posterior-stabilized knee recipients.
January 30, 2018

Anterior Approach THA 90-Day Outcomes Data

The anterior approach to total hip arthroplasty may provide a significant increase in hip function and reduction in pain and narcotics use through the first 90 days post-op vs. a posterior approach.
January 30, 2018

Paradigm Spine Announces 2-Year coflex Study Results

Two-year study results indicate that decompression plus use of Paradigm Spine's coflex® Interlaminar Stabilization® device may enhance the procedure's durability and sustainability vs. decompression alone.
January 19, 2018

Smith & Nephew’s eCAP Shows 97% Decrease in Readmission Rates

Smith & Nephew observed a 97.3% decrease in hospital readmissions following total joint arthroplasties conducted under its eCAP/Episode of Care Assurance Program. 
January 18, 2018

X-Bolt Orthopaedics Reaches Patient Enrollment Milestone

The WHITE Four randomized control trial, comparing the X-Bolt expanding bolt device to a sliding hip screw, has surpassed enrollment of 1,000 patients.
January 17, 2018

MiMedx Enrolls Patients in AmnioFix Phase III Trial

MiMedx commenced enrollment in a Phase III Investigational New Drug clinical trial of AmnioFix® Injectable in the treatment of Achilles Tendonitis.
January 8, 2018

Spineology Duo LIF Postmarket Study Update

First study cases are complete in Spineology's postmarket investigation of the Duo Lumbar Interbody Fusion system.
January 5, 2018

ConforMIS iTotal CR in Mechanical Alignment: Independent Study Results

Study results suggest that use of ConforMI's iTotal CR Knee plus patient-specific instrumentation yields more consistent mechanical alignment than use of patient-specific cutting guides and off-the-shelf implants.
January 4, 2018

Zyga Reports Initial Results in SImmetry SI Fusion Study

Initial outcomes from Zyga's EVSI study indicate a significant reduction in low back pain and opioid use in patients receiving the SImmetry® SI Joint Fusion implant.
January 3, 2018

Zimmer Biomet Reports Positive Study Results with nSTRIDE APS in Knee OA

Zimmer Biomet announced positive results in a pilot study demonstrating safety and promising efficacy from use of the nSTRIDE® Autologous Protein Solution Kit to treat knee OA.
December 1, 2017

Globus Medical SECURE-C Disc vs. ACDF: 7-Year Follow-up

Results of seven-year clinical trial follow-up indicate superiority of Globus Medical's SECURE-C® cervical disc vs. ACDF in the treatment of cervical disc disease.
November 30, 2017

Rotation Medical Bioinductive Implant Study Update

Study results indicate that Rotation Medical's Bioinductive Implant may consistently heal rotator cuff tears, increase tendon thickness and prevent tear progression.
November 2, 2017

Wright Medical INFINITY Postmarket Studies Update

Wright Medical announced the first patient implantation in a multi-center, 10-year U.S. follow-up study of the INFINITY™ Total Ankle.
October 26, 2017

Anika Fully Enrolls Second Phase III CINGAL Trial

Anika Therapeutics completed enrollment in its second pivotal Phase III trial evaluating CINGAL® HA/corticosteroid viscosupplement for the treatment of knee osteoarthritis symptoms.
October 25, 2017

Studies Indicate 5-Fold Reduction in Surgical Complications with Mazor Core Technology

Interim study results demonstrated that surgeries performed with Mazor Robotics' Renaissance Guidance System yielded a 5-fold reduction in surgical complications and a 7-fold reduction in revisions vs. freehand-based, minimally invasive lumbar fusion.
October 23, 2017

FzioMed Receives FDA Approval Oxiplex Study

FzioMed received FDA approval to conduct a small confirmatory study of Oxiplex® synthetic viscoelastic gel, examining its use following lumbar surgery.
October 6, 2017

Study: JNJ’s CareAdvantage Reduces Costs, Improves OR Efficiency

Studies indicate that the CareAdvantage Perioperative Efficiency approach yielded improvements for hip and knee procedures that led to an estimated annual cost savings of >$262,000.
September 22, 2017

Integra Enrollment in Cadence Total Ankle Postmarket Study

Integra LifeSciences implanted the first Cadence® Total Ankle as part of a non-randomized, prospective, multi-center postmarket study.
September 20, 2017

Bone Therapeutics ALLOB Phase I/IIA Delayed-Union Fracture Trial Update

Bone Therapeutics reports positive interim efficacy results and early conclusion of the Phase I/IIA study of ALLOB® allogeneic bone cell therapy in the treatment of delayed-union fractures.
September 14, 2017

Interim Results in ALLOB Phase IIA Spinal Fusion Study

Interim results in a Phase IIA trial with Bone Therapeutics' ALLOB® show evidence of successful spinal fusion and statistically significant improvements at 12 months.
September 12, 2017

Ten-Year Results with Arthrosurface HemiCAP Toe

Ten-year follow-up data indicate excellent outcomes from use of the Arthrosurface HemiCAP resurfacing implant in the treatment of hallux rigidus.
September 7, 2017

MiMedx Can Launch Phase 3 IND Trial for Achilles Tendonitis

MiMedx received permission to proceed with an Investigational New Drug Phase III clinical trial of AmnioFix® Injectable in the treatment of Achilles Tendonitis.
September 5, 2017

Medtronic Launches Study of INFUSE in PLF and TLIF

Medtronic launched a long-term global clinical study to collect prospective data on INFUSE® bone graft in posterolateral and transforaminal lumbar interbody fusion.
August 8, 2017

Study Results: Anika’s HYALOFAST in Knee Cartilage Lesions

Studies indicate that Anika Therapeutics' HYALOFAST® scaffold + autologous adult MSCs present a viable option to treat knee cartilage lesions, regardless of patient age.
August 7, 2017

MiMedx Files for Achilles Tendonitis IND Phase III Clinical Trial

MiMedx filed to initiate an Investigational New Drug Phase III clinical study comparing AmnioFix® Injectable to saline placebo in the treatment of Achilles Tendonitis.
August 2, 2017

MiMedx Plantar Fasciitis Clinical Trial Underway

MiMedx commenced a Phase III study to evaluate AmnioFix Injectable allograft vs. placebo in the treatment of Plantar Fasciitis. 
July 20, 2017

Smith & Nephew, Imperial College to Study Meniscus Function

Smith & Nephew signed a 3-year partnership with Imperial College London to study meniscus function and develop techniques to treat knee injuries caused by sports.
July 17, 2017

Study Results: Inspired Spine’s OLLIF Procedure for Adult Scoliosis

Research indicates that Inspired Spine's OLLIF procedure yielded substantial pain relief and minimal post-op complications in the trestment of adult degenerative scoliosis.
July 10, 2017

Study Results: Providence Medical’s CAVUX and DTRAX Fusion Technologies

Studies indicate that Providence Medical Technology's tissue-sparing cervical fusion devices, CAVUX® Cervical and DTRAX® Expandable cages, yielded improvements in pain, with radiographic confirmation of fusion.
June 13, 2017

ConforMIS Retrospective Study: Customized vs. Off the Shelf Total Knees

Retrospective study results indicate lower adverse events, more rapid discharge, lower follow-up care costs, etc. with custom knee implants vs. standard, off the shelf devices.
May 31, 2017

New ATTUNE Knee Implant Survivorship Data from DePuy Synthes

Independent analysis of 10,605 ATTUNE® Knee procedures showed a cumulative revision rate of 1.3% at 4 years vs. a 1.9% cumulative revision rate for the overall class of total knee replacement.
May 23, 2017

United Orthopedic Enrolls First Patient in U2 Knee Study

United Orthopedic enrolled its first patient in a study of the U2 Knee™, evaluating the system's use in primary total knee arthroplasty.
May 23, 2017

CINGAL Phase III Data Demonstrates Efficacy and Safety to Treat Knee OA Pain

Phase III study results demonstrated that Anika Therapeutics' CINGAL® provided superior immediate and short term OA pain relief after injection vs. hyaluronic acid alone, and superior relief at 26 weeks vs. saline. 
May 18, 2017

Rotation Medical BioInductive Implant REBUILD Study Results

Interim study results indicate that patients receiving Rotation Medical's Bioinductive Implant to treat rotator cuff disease reported statistically significant improvement at six months.
May 17, 2017

Life Spine Announces Approval of Spine Outcomes Study

Life Spine announces the approval of a study to help determine optimal outcomes for Open vs. Minimally Invasive Posterior Lumbar Spine Surgery. 
May 9, 2017

Aesculap Implant Systems Presents Long-term activL Study Data

Studies indicate that, at 5 years, the activ-L® Artificial Disc from Aesculap Implant Systems had a protective effect on the progression of degenerative disc disease at adjacent levels in 91.2% of patients. 
May 8, 2017

Inspired Spine Presents OLLIF Procedure Study Results

Results from a 124-patient study indicate that Inspired Spine's OLLIF procedure was completed at ~2x the speed of an open TLIF, and reduced blood loss by >80% vs. TLIF. 
May 8, 2017

Premia Spine Secures FDA Approval for IDE Study of TOPS

Premia Spine secured FDA approval for a pivotal IDE study of TOPS™, a posterior arthroplasty device for the treatment of spondylolisthesis and spinal stenosis. The study seeks to establish the superiority of TOPS vs. traditional lumbar spinal fusion.
April 25, 2017

Patient Enrollment Complete in Thumb OA Study of Cartiva SCI

Cartiva completed enrollment and treatment of all 50 patients in a multi-center study evaluating the Synthetic Cartilage Implant for thumb base OA.
April 24, 2017

SI-BONE 6-year Clinical Results of iFuse Implant System

Six-year study results on the treatment of SI joint disorders indicated that treatment with conservative management or radiofrequency denervation led to worsened outcomes, while iFuse Implant patients demonstrated superior improvements.
April 18, 2017

Zyga EVoluSIon Study Enrolls 100th Patient

Zyga Technology enrolled the 100th patient in the EVoluSIon trial investigating long-term results and pain reduction following the SImmetry® Sacroiliac Joint Fusion procedure.
April 13, 2017

24-month CT Fusion and Clinical Results for SImmetry SI Joint Fusion

Results from a study of Zyga Technology's SImmetry® Sacroiliac Joint Fusion indicate radiographically-evident fusion as early as 12 months, and increased fusion rates at 24 months. 
April 12, 2017

Clinical Trial Update: Simplify Medical’s Cervical Disc

The first patient has been treated in a pivotal clinical trial of Simplify Medical's Simplify® cervical disc, investigating use in two adjacent levels to treat degenerative disc disease.
April 12, 2017

Study Results: ConforMIS iTotal PS Total Knee

Study results suggest that ConforMIS' iTotal® PS yields knee motion patterns that more closely resemble those of a normal knee than those achieved with a traditional off-the-shelf implant. 
March 28, 2017

Burst Biologics Spinal Fusion Study

Burst Biologics received IRB approval for a U.S. prospective clinical study of BioBurst cellular allograft in spinal fusion.
March 28, 2017

Study Results: RepliCel’s RCT-01 Tendon Repair Clinical Trial

Six-month results from Phase I/II study indicate that RepliCel's RCT-01 fibroblasts demonstrated product safety and clinical potential for tendon regeneration and healing.
March 23, 2017

One-Year Study Results: Percutaneous Application of the IlluminOss System

Study results indicate that percutaneous intramedullary fixation provided by IlluminOss Medical's light curable monomer system can provide stabilization of fractures without open surgery.
March 15, 2017

Study Results: Mesoblast’s Cell Therapy in Degenerative Disc Disease

Studies suggest that a single injection of Mesenchymal Precursor Cells resulted in meaningful improvements in chronic low back pain and function that were durable for at least 3 years.  
March 14, 2017

Study Results: ATTUNE Knee Clinical and Economic Data

Study results demonstrate the clinical and economic value of DePuy Synthes' ATTUNE® knee in a healthcare environment experiencing cost constraint and growing procedure volumes.
March 14, 2017

Collaborative Clinical Study of TracPatch Wearable Device

Consensus Orthopedics and the University of Miami Health launched a collaborative clinical study to evaluate the recovery effectiveness of acute care total knee arthroplasty in patients using the TracPatch wearable device.
March 13, 2017

5-Year Clinical Data on Cartiva Synthetic Cartilage Implant

Five-year results from a clinical trial of the Cartiva Synthetic Cartilage Implant in the treatment of great toe arthritis demonstrated pain relief and functional outcomes equivalent to first MTP arthrodesis at two years post-op.
March 9, 2017

Recruitment Status for ALLOB Delayed-Union Study

Bone Therapeutics completed recruitment of 16 patients in the Phase I/IIA delayed-union fracture study of ALLOB® allogeneic cell therapy product.
March 8, 2017

Bioactive Glass Shown Effective Towards Antibiotic-resistant Bacteria

Studies of BonAlive® indicate that the naturally-antibacterial bioactive glass yields excellent results in the treatment of osteomyelitis, without the use of local antibiotics.
February 28, 2017

Study Results: 98.8% Implant Survivorship of MicroPort Orthopedics Medial Pivot Knee

Results of evaluation of MicroPort Orthopedics' Medial Pivot Knee demonstrated 95.0% satisfaction and 98.8% survivorship at 17 years, with patients reporting high stability and comfort during regular activity.
February 27, 2017

Study Results: Independent Femoral Head Wear Testing

Independent study results indicate that mean wear associated with Amedica's MC2® silicon nitride femoral heads was ~15% lower than a BIOLOX®delta sample after five million cycles.
February 21, 2017

SpineJack FDA Trial Completes Patient Enrollment

Vexim completed enrollment in its FDA clinical trial comparing SpineJack® to balloon kyphoplasty on 152 patients with osteoporotic vertebral compression fractures.
February 8, 2017

AxioMed Completes 2-Year Follow-up for Freedom Lumbar Disc

AxioMed has completed collection and analysis of 2-year follow-up data in its U.S. IDE clinical study of the Freedom® viscoelastic lumbar disc.
February 2, 2017

FDA Approves Expanded 26-week Efficacy Claim for Gel-One to Knee OA Pain

Zimmer Biomet announced FDA approval of an expanded 26-week efficacy claim for single-injection Gel-One® Cross-linked Hyaluronate viscosupplement for the treatment of knee pain associated with osteoarthritis.
January 23, 2017

Study Results: iFuse vs. SI Joint Fixation with Screws

Retrospective study results on patients undergoing sacroiliac joint fusion vs. fixation showed a 5.7% revision rate in fusion patients receiving SI-BONE's iFuse™ vs. a 30.8% revision rate for those undergoing screw fixation.
January 18, 2017

Retrospective Study: Spinal Elements’ Magnum+ ALIF Device With Ti-Bond Coating

Patients in a retrospective study of Spinal Elements' Magnum+® ALIF device with Ti-Bond® coating demonstrated a 96% success rate, with subjects achieving solid arthrodesis at an average of 7.3 ± 2.3 months.
January 12, 2017

Histogenics’ NeoCart Phase I/Phase II Clinical Trial Data

Results from Phase I and Phase II study indicate that Histogenics' NeoCart® tissue-engineered implant is a safe, effective treatment for articular cartilage lesions through 5-year follow-up.
January 4, 2017

Positive Long-Term Follow-Up Data for InSpace System

Long-term follow-up study results indicate that patients with massive rotator cuff tears that were treated with the OrthoSpace InSpace™ system showed improvements in function and pain at 6 weeks, with effects maintained for up to 5 years. 
December 19, 2016

Australian Joint Registry Data for DePuy’s ATTUNE Knee

Implant survivorship data from the 2016 Australian Orthopaedic Association National Joint Replacement Registry confirm positive early results for DePuy Synthes' ATTUNE® Knee. 
December 16, 2016

Study Results: InSpace in the Treatment of Massive Rotator Cuff Tears

Initial study results indicate that patients undergoing the InSpace™ procedure to treat massive rotator cuff tears experienced durable improvements in shoulder function and reductions in shoulder pain at one year.
December 15, 2016

SpinalCyte’s IRB Approval for Phase I Clinical Trial

SpinalCyte received IRB approval to commence Phase I clinical trials with its CybroCell dermal fibroblast cell product in the treatment of degenerative disc disease.
December 15, 2016

Study Results: OrthoTrophix TPX-100 in Knee OA

OrthoTrophix announced results of the first proof of principle study of TPX-100 in bilateral knee osteoarthritis, showing improvements at 6 and 12 months in key knee-related outcome measures.
December 15, 2016

U.K. National Joint Registry Analysis of Zimmer Biomet Trabecular Metal Cups

Zimmer Biomet announced positive outcomes associated with use of Trabecular Metal™ Cups in >9,500 revision hip arthroplasty cases, as reported in data from the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man.
December 9, 2016

Study Results: Biomatlante’s MBCP+ Synthetic Bone Graft and MSCs

Study results demonstrated a high rate of clinical success from a combination of Biomatlante's MBCP+™ synthetic bone graft plus mesenchymal stem cells, particularly in the treatment of long bone non-union fractures.
December 9, 2016

Three-Month Interim Safety Data from Phase I Clinical Trial of AlloJoin

Three-month safety data from a Phase I clinical trial in China for Cellular Biomedicine's AlloJoin™ off-the-shelf allogeneic stem cell therapy in the treatment of knee osteoarthritis demonstrated a safety and tolerability profile of AlloJoin in the three doses tested, with adverse events similar to that of earlier autologous trials. The trial is slated for completion in 3Q17.
December 6, 2016

JAZZ Band Clinical Results in Hypokyphotic Idiopathic Scoliosis Patients

Study results indicate that Implanet's JAZZ sublaminar bands offered a safe, efficient alternative to traditional techniques at up to 34 months in the treatment of complex hypokyphotic thoracic scoliosis.
December 6, 2016

Study Results: EXOGEN Ultrasound Bone Healing System

Study results indicate that the latest-generation design of Bioventus' EXOGEN® Ultrasound Bone Healing System improves patient compliance by 10%, with overall compliance at a minimum of 76%.
December 1, 2016

Study Results: Generic Orthopaedic Implants Clinically Equivalent, Provide High Value

Independent study results indicate comparable clinical outcomes with the use of generic vs. conventional orthopaedic trauma implants, with savings averaging US $1,197 per case. Generic implants were provided by The Orthopaedic Implant Company.
November 29, 2016

New UK Joint Registry Data for DePuy Synthes ATTUNE Knee

DePuy Synthes announced new clinical evidence indicating positive performance of the ATTUNE® Knee, indicating a favorable comparison to the class of cemented total knee systems.
November 2, 2016

Medovex Announces Successful Largest Living Tissue Population Test to Date

Medovex conducted a successful live tissue test of the DenerveX™ system under the most stringent standards required by FDA and other regulatory agencies. The device is intended to treat pain associated with facet joint syndrome.
October 28, 2016

Pre-clinical Study Results: Stryker’s 3D-printed Tritanium PL Interbody Cage

Results from a pre-clinical interbody fusion study of Stryker Spine's 3D-printed Tritanium PL Interbody Cage demonstrated statistically superior range of motion, bone in-growth and greater average construct stiffness vs. PEEK and titanium plasma-sprayed PEEK cages.
October 27, 2016

Positive Comparative Data from 7-Year Follow-Up Study of Mobi-C

Seven-year outcomes study data demonstrated statistical superiority of Zimmer Biomet's Mobi-C® Cervical Disc vs. 2-level ACDF in overall success. 
October 20, 2016

Randomized Study Results: Safe Orthopaedics

Randomized study results indicate that Safe Orthopaedics' single-use spine surgical instruments yielded an 80% decrease in pre- and post-operative times.
September 26, 2016

Regentis Receives IDE Approval for Pivotal GelrinC Clinical Trial

Regentis Biomaterials received FDA Investigational Device Exemption approval to initiate a pivotal Phase III clinical study of its GelrinC procedure to treat focal knee cartilage defects.
September 21, 2016

Study Results from Inspired Spine’s MIS Direct Thoracic Interbody Fusion Procedure

Study results indicate that the minimally invasive direct thoracic interbody fusion or MIS-DTIF approach, offered by Inspired Spine, was shown to alleviate back pain in patients with degenerative disc disease or herniation.
September 19, 2016

OSTEOGROW Research Update

OSTEOGROW, an EU-funded collaborative research project, is investigating a new bone regeneration therapy based on autologous blood + BMP-6 for use in applications requiring partial bone replacement, without the need for secondary interventions. 
September 12, 2016

Orthofix Enrolls First Patient in Knee OA Study

Orthofix enrolled the first patient in a study evaluating use of Physio-Stim pulsed electromagnetic field technology to treat knee osteoarthritis.
August 24, 2016

2-Year Results from SI-BONE iFuse INSITE Trial

Two-year results from a randomized, controlled trial in the management of sacroiliac joint dysfunction revealed that SI-BONE's iFuse yielded more rapid improvements in pain, disability and quality of life vs. non-surgical treatment.
August 15, 2016

Clinical Study Results: ConforMIS iTotal CR Customized Knees

Study results indicate that total knee patients receiving ConforMIS' iTotal® CR outperformed recipients of off-the-shelf implants in terms of length of stay, discharge within 24 hours, discharge to home vs. a SNF, etc.
August 9, 2016

BONESUPPORT Receives FDA Approval to Initiate IDE Clinical Study

BONESUPPORT received FDA approval to launch an Investigational Device Exemption study of CERAMENT G bone graft substitute in the treament of open diaphyseal tibial fractures.
July 26, 2016

Pre-clinical Study Results: Multipotent Adult Progenitor Cells on an Allograft Scaffold

Pre-clinical studies suggest that multipotent adult progenitor cells (MAPCs), such as the technology used in RTI Surgical's map3® Cellular Allogeneic Bone Grafts, exhibited a more robust angiogenic protein release profile vs. mesenchymal stem cells in vitro.
July 6, 2016

Interim U.S. Study Results: ConforMIS’ iTotal CR

Interim results from a U.S. 300+ patient multi-center prospective study of ConforMIS' iTotal CR total knee indicate that 92% of patients were satisfied with their procedures at one year. 
July 6, 2016

Preclinical Study Validates Science Behind AlloSource AlloStem Cellular Bone Allograft

Preclinical data on adipose-derived mesenchymal stem cells in a rat model, using technology similar to AlloSource's AlloStem® Cellular Bone Allograft process, showed bone formation within a critical-sized defect in all study subjects.
July 6, 2016

Two-year Clinical Results for Spineart’s Baguera C Cervical Disc

Study results indicate that patients treated with Spineart's BAGUERA® C cervical disc in 1- or 2-level arthroplasty exhibited good mobility at treated and adjacent levels, disc height restoration and evidence of adjacent level preservation.
June 1, 2016

Pre-Clinical Study Highlights CERAMENT’s Bone Remodeling Properties

Pre-clinical study results demonstrated that BONESUPPORT's CERAMENT™, loaded with rhBMP-2 + zoledronic acid in very low doses, was able to quantitatively/qualitatively generate a high amount of mineralized bone volume.
May 23, 2016

Active Implants Announces 1st Meniscus Replacement in SUN Clinical Trial

Active Implants announced the first meniscus replacement in the SUN (Safety Using NUsurface®) clinical trial for patients with persistent knee pain following medial meniscus surgery.
May 19, 2016

Medacta Reports on Device Utilization

Results from a 421-patient study revealed a 97.75% survival rate at 5 years for Medacta's AMIStem hip implant. AMIStem has been implanted >100,000 times, to date.
May 9, 2016

Results from Study of Moximed’s Atlas Knee

Study results suggest that Moximed's Atlas™ knee provided rapid, clinically-effective pain relief for patients with early knee OA in the pre-arthroplasty disease stage.
April 20, 2016

Study Results Show Benefits of SI Joint Fusion after Two Years

Results from a 2-year study of SI-BONE's iFuse implant for sacroiliac (SI) joint fusion show that improvements in SI joint pain, disability and quality of life at 6 and 12 months were maintained to 2 years.
March 30, 2016

Clinical Studies Compare ConforMIS iTotal CR Knee to Off-the-shelf Devices

Study results demonstrated that patients implanted with ConforMIS' iTotal® CR customized total knee exhibited more natural knee kinematics vs. those receiving an "off-the-shelf" total knee.
March 30, 2016

Independent Peer-Reviewed 5-Year Follow-Up: 2-Level Cervical Disc Replacement vs. ACDF

Results from 5-year clinical study comparing cervical total disc replacement (LDR's Mobi-C) with anterior discectomy and fusion to treat 2-level degenerative disc disease indicated overall success rates of 61% and 31% for cTDR and ACDF, respectively.
March 29, 2016

Bone Therapeutics Reports Initial Efficacy from PREOB® Phase IIA Trial

Initial 12-month efficacy results from a Phase IIA trial demonstrate positive effects on pain and osteoporosis blood markers from a single administration of Bone Therapeutics' PREOB® autologous osteoblastic cell therapy.
March 29, 2016

Results from 6-month ActiPatch Product Observation Study

Results from a 6-month study observing BioElectronics' ActiPatch® musculoskeletal pain therapy device indicated an average 61% reduction in pain for >90% of participants, a decrease in doctor visits, etc. 
February 25, 2016

Study of PEMF in Disc Degeneration

Study results suggest that use of pulsed electromagnetic field therapy, such as Orthofix's Physio-Stim®, may reduce cellular inflammation and degredation in intervertebral disc cells.
February 24, 2016

Study Results: ReLeaf Catheter Supports Cost-effective Post-op Pain Management

Preliminary study results indicate that the Vital 5 ReLeaf Catheter improved pain scores and reduced post-op narcotic use following orthopaedic and spinal surgeries, and may support a transition to outpatient procedures.
February 17, 2016

ALLOB Phase IIA Spinal Fusion Trial Update

Bone Therapeutics has treated 12 patients in the ALLOB® Phase IIA spinal fusion trial, and reports no safety concerns.
February 15, 2016

Study results: Episealer may stop or significantly slow the process leading to OA

Study results suggest that a permanent bond may form between cartilage and the hydroxyapatite coating of Episurf's Episealer® device, suggesting that implantation may stop or significantly slow the progression to OA.
February 10, 2016

Regentis Biomaterials Raises $15MM for U.S. Pivotal Clinical Trial

Regentis Biomaterials closed a US $15MM Series D investment round. Funds will primarily support a pivotal U.S. clinical trial of GelrinC®, a cell-free implant for the treatment of articular knee cartilage injuries.
February 10, 2016

Five-Year Results of Mobi-C Cost Utility Analysis

Studies concluded that, for patients with 2-level degenerative disc disease, cervical total disc replacement appears to be highly cost-effective vs. ACDF, and supports greater quality of life at less cost. 
February 3, 2016

Histogenics Completes 50% Enrollment in NeoCart Phase III Trial

Histogenics has completed >50% of the required enrollment in its ongoing NeoCart® Phase III clinical trial in the treatment of knee cartilage defects.
January 11, 2016

CartiHeal Raises $15 Million

CartiHeal completed a US $15MM financing round. Funds will support ongoing manufacturing scale-up, EU product commercialization in 2017 and clinical studies in new therapeutic areas for Agili-C™ cartilage regeneration technology.