The transaction includes GUIDOR bone graft substitutes known as easy-graft and calc-i-oss, and builds on the company's strategy to expand its technologies.
All Ossifix pins, screws and plates are single-use surgical kits with all necessary instruments and are based on long-term clinical experience and O.R. use.
STAR is one of the first total ankle systems in the market and the Silicone, Surface Replacement and TACTYS finger portfolio holds a leading global market position.
Following acquisition of parent company FH Ortho, Spine Innovations is fully independent and dedicated to worldwide sales deployment of ESP disc replacements.
The acquisition underscores Olympus' plan to expand orthopedic minimally invasive surgery products, both organically and through mergers and acquisitions.
Globus Medical acquired all of Evonik's shares in Synoste, a Finnish startup. Synoste's limb-lengthening technology could bolster Globus' trauma business.
To clear regulatory issues related to its purchase of Wright Medical, Stryker proposed DJO as a buyer for certain ankle and finger joint replacement lines.
Surgalign Holdings will enter the digital surgery space by acquiring HoloSurgical and it's Augmented Reality and Artificial Intelligence (ARAI) platform.
Fibrinet enables safe and rapid preparation of Platelet-Rich Fibrin Membrane and Platelet-Rich Fibrin Gel from a small sample of blood at the point of care.
WishBone acquired assets of Back 2 Basics Direct and Orbbö, companies focused on R&D and commercialization of implants and instruments for spinal fusion.
Medicrea announced that it entered into an agreement to be acquired by Medtronic at a price of €7 (USD $8.01) per share with a 2020 estimated close date.
This is the next step of Conventus' transformation as it expands distribution channels and builds its portfolio with product development and acquisitions.
OrthoPediatrics acquired ApiFix and its minimally invasive deformity correction system, MID-C, for non-fusion treatment of progressive adolescent idiopathic scoliosis.
Alphatec/ATEC entered into an agreement to acquire EOS imaging for nearly USD $122 million in cash and equity. The transaction is slated to close in 3Q20.
With the acquisitions of Parcus Medical and Arthrosurface, Anika looks ready to complete a major step in its five-year strategic plan to become a leader in joint preservation and restoration.
Johnson & Johnson, parent to DePuy Synthes Companies, entered into an agreement to acquire the remaining ownership stake in Verb Surgical. The transaction is expected to close in 1H20.
Advanced Medical Solutions acquired Biomatlante, developer, and manufacturer of orthobiologic products with application in joint reconstruction, spine, trauma, and sports medicine procedures.
Collagen Matrix, manufacturer of collagen- and mineral-based products for tissue and bone repair and regeneration, was acquired by Linden Capital Partners.
Boston Scientific closed its previously-announced acquisition of Vertiflex, developer of the Superion® Indirect Decompression System to treat lumbar spinal stenosis.
Astura Medical partnered with Academy Medical for contracting within the U.S. Department of Defense and Veterans Affairs for sales of spinal instrumentation and implants.
OrthoPediatrics acquired Vilex, with its Orthex Hexapod circular fixation technology and x-ray planning software, for USD $60MM. Vilex posted 2018 revenue of $11.8MM, mostly derived from U.S. sales.
Of the 20 OEM-related M&A announcements we've covered in 2019 thus far, seven have related to the spine market. Of those, three were announced in rapid succession within this quarter. Let's see who bought whom, and what they got: Medtronic/Titan Spine, Boston Scientific/Vertiflex and WishBone Medical/CSpine.
HealthpointCapital acquired a controlling stake in CrossRoads Extremity Systems, developer of procedure-specific, sterile-packed implants and instrumentation for foot/ankle fixation.
Boston Scientific entered into a definitive agreement to acquire Vertiflex, developer of the Superion® Indirect Decompression System. The transaction is slated to close in late 2Q19.
Axolotl Biologix, a developer of regenerative medicine products, was acquired by a private equity firm. The company is preparing for FDA clinical trials of biologic products that have a range of applications in numerous segments, including orthopedics.
Brainlab has acquired Medineering, a developer of application-specific robotic technologies. The move supports Brainlab's growing market reach into ambulatory surgery centers.
As was shown last week at AAOS, companies are taking strides to connect their devices with technologies that support improved patient outcomes. That connection can come in the form of M&A activity - which certainly applies to transactions announced over the month of March in joint replacement.
Stryker acquired OrthoSpace, maker of the InSpace device to treat rotator cuff tears, in an all-cash transaction for an upfront payment of US $110MM and future milestone payments of up to an additional $110MM.
Smith & Nephew will acquire Brainlab's orthopedic joint reconstruction business, enabling both companies to accelerate R&D in digital surgery and augmented reality.
THINK Surgical and United Orthopedic Corporation will pursue reproducible outcomes in total knee replacements, pairing THINK's Active Robotic System and UNITED's U2 knee.
Medacta and the Geisinger health system partnered to pilot a knee replacement lifetime guarantee, in which the pair will stand behind the full cost of care associated with surgeries over a patient's lifetime.
Smith & Nephew entered into an agreement to acquire Osiris Therapeutics, developer of regenerative medicine products including skin, bone graft and articular cartilage substitutes. The transaction is expected to close in 2Q19.
Generex Biotechnology entered into letters of intent to acquire Pantheon Medical “ Foot & Ankle, manufacturer of the FDA-cleared Balanced Plating System, and distributor Medisource Partners.
LimaCorporate and the Hospital for Special Surgery are co-founding an additive manufacturing 3D printing facility to create custom orthopaedic implants in a hospital setting.
Smith & Nephew entered into an agreement to acquire Ceterix Orthopaedics, developer of NovoStitch®Pro Meniscal Repair, for up to US $105MM. The transaction is expected to close in early 2019.
WishBone Medical was granted a global, non-exclusive license for sale of a guided growth plating system to treat pediatric deformed limbs. Product launch is slated for 1Q19.
WishBone Medical acquired Response Ortho, a manufacturer of external and internal fixation and deformity correction products for the pediatric orthopaedic market.
Innovasis entered into a private-label agreement with Stability Biologics that includes access to Physio® bone allograft. Product launch is expected by year-end.
CellRight Technologies, a Tissue Regenix company, entered into an agreement granting Arthrex distribution rights to its BioRinse bone portfolio in Europe.
WishBone Medical acquired Red Star, a contract manufacturer, to provide sterile packaging and plastic injection molded single-use instruments for the pediatric orthopaedic market.
Merger and acquisition activity is shaping the broader orthopedic supply chain base, with contract manufacturers of all sizes transforming in the last decade to keep pace with their scaling device company customers. We've identified three M&A trends in this portion of the market.
NuVasive Clinical Services was awarded a three-year, sole source supplier contract for Intraoperative Neuromonitoring with Premier, effective November 2018.
NuVasive entered into a strategic partnership with Biedermann Technologies to integrate proprietary screw technology into NUVA's RELINE® portfolio, for 1H19 launch.
Amedica completed the sale of its spine business to CTL Medical, which is now exclusive owner of the metal and silicon nitride spine product portfolio.
Bioventus received ANVISA approval to market DUROLANE® single-injection in Brazil to treat hip osteoarthritis. Pfizer will serve as its exclusive distribution partner.
4WEB Medical entered into an exclusive partnership with Lattus Spine and TeDan Surgical Innovations to co-market a turnkey Total Lateral Solution, with retractor and implant.
Medtronic entered into a definitive agreement to acquire Mazor Robotics for US $1.64BB in cash in a transaction that is slated to close in January 2019.
We've tracked 31 mergers and acquisitions in the spine space from 2017 through mid-September 2018...with eight of them happening in just the last four weeks. The global spine market comprises nearly 300 companies; players need broad portfolios or novel technologies to vie for market share today.
Stryker entered into a definitive agreement to acquire instrument manufacturer Invuity for US $190MM in equity. The transaction is slated to close in 4Q18.
Stryker entered into a definitive merger agreement to acquire K2M for ~US $1.4BB in cash. The transaction is slated to close in 4Q18. For 2017, K2M posted revenue of $249.3MM, +8.8% vs. 2016.
Wright Medical is acquiring Cartiva, a manufacturer of the Synthetic Cartilage Implant to treat arthritis in the great toe, for US $435MM. The transaction is expected to close in 4Q18.
Ember Therapeutics plans to divest its OP-1 bone morphogenetic protein (BMP-7) portfolio to Viscogliosi Brothers. The transaction is slated to close by 4Q18.
NuVasive and Siemens Healthineers entered into a Spine Precision Partnership to integrate the Pulse surgical automation platform with Siemens' Cios Spin mobile 3D C-arm.
Bioventus entered into a definitive agreement to divest its next-gen bone morphogenetic protein development program to Viscogliosi Brothers. The transaction is slated to close in 3Q18.
Medigus entered into a development agreement with A.M. Surgical to develop an integrated visualization device to complement Stratos, A.M. Surgical's product for endoscopic carpal tunnel release.
BONESUPPORT entered into an agreement with Collagen Matrix on U.S. sales of bone graft substitute products through its own U.S. distribution network, beginning in 4Q18.
DePuy Synthes signed a definitive agreement to acquire the assets of Medical Enterprises Distribution, developer of the ME1000 Surgical Impactor for use in hip replacement. The transaction is slated to close in 2Q18.
Integer entered into an agreement to sell its Advanced Surgical and Orthopedics lines to MedPlast, a global services provider to the medical device industry, for US $600MM in cash. The transaction is expected to close in 3Q18.
Cadence, global provider of high-precision components and finished devices for orthopaedic and other markets, signed a definitive agreement to be acquired by private equity firm Kohlberg & Company.
NN entered into a definitive agreement to acquire Paragon Medical for US $375MM in cash. For 2017, Paragon posted revenue of $141.0MM. The transaction is slated to close during 2Q18.
KFx Medical entered into a license agreement allowing Wright Medical Technology to promote products and techniques for knotless double row rotator cuff repair, as claimed in U.S. Patent No. 7,585,311.
Orthofix entered into a definitive agreement to acquire Spinal Kinetics for US $45MM in cash plus up to $60MM in potential milestone payments. The transaction is expected to close in 2Q18.
Alphatec Spine acquired SafeOp Surgical, provider of neuromonitoring technology, for an initial outlay of US $15MM, and also announced new leadership appointments.
Onkos Surgical signed a 4-year agreement with 3D Systems to develop and advance patient-specific tools for use in tumor-related reconstruction in the pelvis and long bones.
CellRight Technologies signed a long-term, multi-year distribution agreement with Arthrex for CellRight's orthobiologic products for use in orthopaedic, spine and foot/ankle procedures.
Johnson & Johnson will collaborate with Trinity College Dublin to open a 3D bioprinting research lab, initially focusing on orthopaedic-related projects.
Johnson & Johnson Medical Devices is acquiring Orthotaxy, developer of a robotic-assisted surgery solution in early-stage development for total and partial knee replacement.
Implanet entered into a U.S. distribution agreement with Aegis Spine, subsidiary of L&K Biomed, to complement Implanet's commercialization activity in the region.
Wright Medical acquired IMASCAP, developer of the technology that drives BLUEPRINT™ 3D surgical planning software, for US $88.8MM in cash, stock and milestone payments.
NuVasive entered into a definitive agreement to acquire SafePassage, provider of intra-op neurophysiological monitoring services. The company will join NUVA's Clinical Services business in a transaction slated to close in January 2018.
curasan entered into an exclusive agreement with Implantcast for distribution of CERASORB bone regeneration products in Austria, Germany and Switzerland.
Arthrosurface acquired IP from WASAS pertaining to an acellular dermal stabilization allograft device that may address various orthopaedic therapeutic challenges.
Stryker acquired Vexim, developer of the SpineJack® expandable vertebral compression fracture implant, for ~US $191.0MM. The transaction is expected to close in 4Q17.
Smith & Nephew entered into a definitive agreement to acquire Rotation Medical for US $125MM in initial cash. The transaction is expected to close by year-end.
ORTHOWORLD estimates that global orthobiologic product sales account for ~10% of the orthopaedic market's revenue, overall. In 2016, that translated to just over $4.9 billion, an increase of 3% vs. 2015. For 2017 and into 2019, we're projecting similar growth.
Mazor Robotics entered Phase II of its strategic partnership with Medtronic, which will now take on exclusive global distribution of the Mazor X surgical assistance platform.
OrthoPediatrics entered into an agreement for exclusive U.S. distribution of Mighty Oak Medical's FIREFLY® pedicle screw navigation guides in pediatric hospitals.
Supplier companies have been involved in 17 of the 33 mergers and acquisitions that have closed in the orthopaedic space as of August 15, according to our tracking of activity. This activity comes in direct response to device company consolidation.
DePuy Synthes entered into an exclusive U.S. agreement with JointPoint to co-market a surgical navigation platform for total hip replacement, beginning in 2H17.
Bone Biologics entered into an exclusive license agreement with UCLA for global application of NELL-1 protein in the treatment of osteoporosis and trauma, through a technology transfer.
OrthAlign announced first KneeAlign® total knee arthroplasties completed in Panama, alongside entrance into a distribution partnership with Ortosistemas.
Premier is now offering Bioventus' full surgical orthobiologics product portfolio to its U.S. membership, comprising 3,750 hospitals and >130,000 provider organizations.
Zimmer Biomet entered into an agreement to license patents from Bonutti Research, supporting the development of the Rosa® robotic total knee application.
Seikagaku entered into a basic co-development and marketing collaboration with Ono Pharmaceutical in Japan for SI-613 for the treatment of osteoarthritis.
Xtant Medical (XTNT) entered into a licensing agreement with Sites Medical for use of OsteoSync™ Ti porous titanium scaffold technology with XTNT's spinal products.
DePuy Synthes was awarded a contract from the U.S. Department of Defense to supply up to US $260MM worth of orthopaedic products to global U.S. military medical facilities.
Vericel entered into a license agreement whereby Innovative Cellular Therapeutics will obtain exclusive rights to develop and distribute Carticel® and MACI® in Southeast Asia.
Genstar Capital sold Tecomet, a global supplier of high-precision manufacturing solutions for orthopaedic implants, instruments and sterilization cases/trays, to Charlesbank Capital Partners.
TITAN Metal Fabricators acquired select assets of Edge International, distributor of raw materials used in the manufacture of implants and instruments for the orthopaedic, spine and trauma markets.
7D Surgical entered into exclusive partnerships with Surgical One and DB Surgical for U.S. distribution of its Machine-Vision Image Guided Surgery platform for spine procedures.
DePuy Synthes acquired 3D printing technology from Tissue Regeneration Systems to offer patient-specific, bioresorbable implants for orthopaedic and CMF applications.
United Orthopedic acquired A-Spine Asia, developer of spinal fixation, osteoplasty and vertebral body replacement systems, for US $20.0MM. For 2016, A-Spine posted revenue of $11.3MM.
Audax Medical was granted an exclusive worldwide license from Northeastern University for a self-assembling, arginine-rich nanomolecule for development in tissue regeneration.
OMNIlife science signed an agreement granting exclusive license to Global Orthopaedic Technology to manufacture and market the APEX™ Knee in Australia, New Zealand and South Africa.
Sussex Wire, manufacturer of cold formed components for a variety of industries, acquired Marox, a manufacturer of orthopaedic implants and instruments.
Zimmer Biomet has publicly unveiled Signature Solutions, and is previewing a concept device that will support personalization and intelligent instrument technology through surgical robotics.
Amend Surgical entered into an exclusive agreement with The University of Florida Research Foundation to license patents for the development of Biomimetic Bone.
Implanet announced integration of its Jazz Claw device into the Australian Register of Therapeutic Goods and entry into an exclusive partnership with Device Technologies for product distribution in Australia and New Zealand.
Proper implementation post-acquisition-close will allow your supply chain to deliver immediate and long-term value, and avoid integration delays and disruptions.
The U.S. hospital landscape steadily continues to be shaped by consolidation that is forced by competition, declining reimbursement and public and private payor cost and control measures. As these trends are expected to endure at least through the next decade, it's imperative that you understand what your hospital customer base will look like several years from now.
Vertebral Technologies entered into a GPO contract to provide modular interbody fusion devices to member facilities of Resource Optimization & Innovation/ROi.
Trice Medical entered into an agreement with Pacific Medical for multi-state distribution of the mi-eye 2™ in-office arthroscopic diagnostic tool in the U.S.
SpineSource entered into a long-term exclusive U.S. agreement to distribute Kisco International's L-Varlock® Expandable Lumbar Cage for vertebral interbody fusion.
Exactech has restructured its Spine & Biologics segment, divested its spine product assets to ChoiceSpine and announced restructuring charges related to ex-U.S. operations. Terms were not disclosed.
DePuy Synthes entered into an exclusive agreement with Pacira Pharmaceuticals for U.S. co-promotion of EXPAREL® local analgesic across its joint reconstruction, spine, sports medicine and trauma businesses.
The primary responsibility of the supply chain team post-M&A is the assurance of uninterrupted upstream and downstream product supply. These essential steps will assist you in identifying supply chain risk and developing a plan to minimize that risk.
Bovie Medical entered into a global sales channel partnership agreement with CONMED for its PlazXact™ Ablator, which will be marketed as the UltrAblator Bipolar® series effective in late 1Q17.
Orthocell entered into a research collaboration agreement with DePuy Synthes Products for the Ortho-ATI® stem cell treatment for tendon and ligament regeneration.
OssDsign entered into new commercial partnerships covering distribution of its products for cranial repair and facial bone reconstruction in Italy, Spain, Switzerland, Austria and The Netherlands.
DePuy Synthes entered into an asset purchase and development agreement with Interventional Spine, addressing expandable fusion cages and a facet screw system for open and percutaneous spine surgery.
AxioMed modified terms of a previously-signed 15-year exclusive license agreement with DSM Biomedical, holder of the patent on polymer technology used in AxioMed's viscoelastic disc replacement.
OrthoMend Research acquired from Temple University researchers an exclusive license to develop novel absorbable bone fixation and regenerative repair technologies for commercial use.
MedPlast, parent company of OrthoPlastics, was acquired by strategic investor Water Street Healthcare and JLL Partners, a middle-market private equity firm. Terms were not disclosed.
HD Surgical, a custom orthopaedic surgical instrument and implant manufacturer, recently acquired certain assets of PAK Manufacturing, a maker of custom and specialty handheld surgical instruments.
General Electric reached an agreement to acquire a 75% stake in Concept Laser, manufacturer of powder bed-based laser additive manufacturing machines, for 549MM (~US $599MM).
Zimmer Biomet acquired RespondWell® telerehabilitation technology, designed to provide personalized, clinician-supervised post-surgical physical therapy in a patient's home.
NuVasive is introducing an Integrated Global Alignment™ platform that is expanded to support cervical alignment. Further, the company acquired LessRay software technology from SafeRay Spine.
Spinal Elements and Mighty Oak Medical will co-market the FIREFLY® surgical guidance system, comprising patient-matched bone models and intra-op pedicle screw guides created via 3D printing.
Strategic transactions year to date in 2016 represent participants from OEMs, Suppliers, Distributors and Private Equity, with values ranging from $10 million to $1 billion.
Avoid disruptions in customer service and financial performance by reviewing the people, processes and supporting systems of upstream and downstream supply chains.
Data collection is paramount to the success of any orthopaedic device. What happens to the much-coveted postmarket data/initiative during and after a merger or acquisition? We posed this question to Vicki Anastasi, Vice President & Global Head, Medical Devices & Diagnostics Research with ICON plc.
Isto Technologies acquired Arteriocyte Medical Systems, forming Isto Biologics. The new entity will offer evidence-based solutions for spine and orthopaedic applications. Terms were not disclosed.
Tecomet acquired Mountainside Medical, a manufacturer of instruments for minimally invasive surgery and orthopaedic/neurosurgical implants and instruments.
The Musculoskeletal Transplant Foundation is now sole tissue provider for Spineology's allograft product lines, including the newly-launched Incite™ Cortical Fiber bone graft.
Spineway signed a 5-year agreement with TINAVI Medical for distribution of spinal implants and instruments in China. TINAVI's TiRobot™ is reported to be the only surgical robot capable of addressing surgery on all spinal regions.
Stryker entered into a definitive agreement to acquire Instratek, provider of implants and minimally invasive soft tissue recession instrumentation for foot, ankle and upper extremity procedures.
In2Bones SAS has merged with In2Bones USA, its largest distributor, to form i2b, a global company serving the upper and lower extremities orthopaedic markets.
Norgine Ventures entered into a definitive agreement to acquire SpineVision. The partnership will support SpineVision's research and development for commercialization of products combining dynamic stabilization and a minimally invasive, percutaneous approach, such as Flex+2 and LUMIS.
Ferring Pharmaceuticals acquired exclusive development and commercialization rights to Seikagaku's SI-6603 injectable condoliase, a potential treatment for lumbar disc herniation, for up to US $95.0MM in upfront cash plus milestone payments.
SeaSpine entered into a definitive agreement to acquire NLT Spine, developer of minimally invasive surgery devices. SeaSpine's commercial launch of the first NLT product is expected in 1H17.
Zimmer Biomet acquired CD Diagnostics, developer of immunoassays and biomarker testing to inform treatment decisions. Financial terms were not disclosed.
Biomedical Structures, manufacturer of biomedical textile implants with application in orthopaedics, was acquired by Confluent Medical Technologies, a contract manufacturer of Nitinol components and kyphoplasty balloons. Terms were not disclosed.
Globus Medical entered into an agreement to acquire the ex-U.S. operations and distribution channels of Alphatec (ATEC) for US $80.0MM in cash. ATEC posted 2015 ex-U.S. revenue of $70.7MM.
Zimmer Biomet announced its plans to acquire Medtech, provider of surgical systems including the ROSA™ Spine robotic-assistive device for minimally invasive surgery.
Wright Medical received a binding offer under which Corin Orthopaedics would acquire Wright's hip/knee business for 29.7MM in cash (~US $33MM). The proposed transaction is expected to close by early 4Q16.
Merit Medical Systems, manufacturer of proprietary disposable devices used primarily in cardiology, radiology and endoscopy, acquired DFINE in a merger transaction for ~US $97.5MM in cash.
During 1H16, seven of the eight largest orthopaedic device companies confirmed or completed acquisitions or divestitures spanning nearly every orthopaedic market segment. Here we present a full list of M&A transactions from the first half of the year.
Zimmer Biomet entered into a definitive agreement to acquire LDR for US $37/share in cash, for a transaction valued at ~$1.0BB with an expected 3Q16 close.
Medtronic acquired Responsive Orthopedics, a start-up focused on sales of low-cost hip and knee replacements. A primary knee is slated for commercial U.S. availability within 1H17, followed by a primary hip in 1H18.
NuVasive (NUVA) entered into a definitive agreement to acquire Biotronic NeuroNetwork, a U.S. provider of intraoperative neurophysiological monitoring services, for US $98MM in cash.
Mazor Robotics entered into strategic agreements with Medtronic for equity investment and for co-development/potential global distribution of certain Mazor products.
Novastep signed an agreement with Vivex Biomedical to launch bioSTART® Tissue Repair products, offering amniotic membranes and liquid to support foot and ankle procedures in the U.S.
Zimmer Biomet closed its previously-announced acquisition of Cayenne Medical, a manufacturer of soft tissue repair and reconstruction products for the knee, shoulder and extremities.
DePuy Orthopaedics has acquired BioMedical Enterprises, a manufacturer of Nitinol orthopaedic implants for small bone fixation to treat bunions, hammertoes, hand/wrist deformities, etc.
Histogenics acquired development and commercialization rights to NeoCart® for the Japanese market from its partner, Purpose Co. NeoCart autologous cell therapy is designed to treat knee cartilage defects.
Private equity firm Kohlberg & Company has acquired majority ownership of Amendia, and will support its growth initiatives from a US $1.6BB private equity fund.
Stryker acquired Stanmore Implants Worldwide in an all-cash transaction for £35.6MM (~US $52MM). Stanmore Implants' portfolio comprises patient-specific and off-the-shelf implant systems for limb salvage.
BD sold its vertebral augmentation assets, including all AVAmax®, AVAflex®, AVAtex® and AVAprep® branded products, to Stryker. Financial terms were not disclosed.
LISI Medical, a contract manufacturer, signed an agreement to acquire Alcoa Remmele for 90MM (~US $102MM). The transaction is expected to close in 2Q16. Remmele posted 2015 revenue of $70MM.
Stryker Spine acquired SafeWire's product portfolio, including the Y-Wire guidewire and Tiger Jamshidi Needle for use in minimally invasive spine surgery.
aap Implantate sold its biomaterials unit to an undisclosed private equity firm for 36MM (~US $40.3MM). Upon closing, aap will proceed as a pure-play trauma entity.
Intellijoint Surgical entered into a strategic partnership with Corin for Australia distribution of the intellijoint HIP™, to complement Corin's Optimized Positioning System™ technology.
OrthoSensor entered into a partnership with IM-Tech to support R&D collaboration, manufacturing and investments in electronics technology in the global commercialization of the VERASENSE™ sensor.
NuVasive entered into a definitive agreement to acquire Mega Surgical, its exclusive distributor in Brazil. The transaction is expected to close within 1Q16.
EOS imaging entered into a co-promotion agreement whereby Stryker's European Spine business will promote EOS imaging's platform to existing and prospective customers in the U.K.
Lima Corporate entered into an Innovation Alliance Agreement with the Hospital for Special Surgery. New product co-developments include a Trabecular Titanium total elbow and an advanced acetabular cup.
LifeNet Health and Arthrex signed a new long-term agreement to provide allograft implants and instrumentation to surgeons and explore new applications, such as opportunities in cartilage repair.
Bone Therapeutics extended its collaboration with Kasios to combine ALLOB® bone cell therapy with a 3D-printed synthetic cage intended to support the spinal fusion process.
Exactech acquired Exactech Australia, an independent importer and distributor of Exactech's orthopaedic implants, instrumentation and surgical technology.
Bioventus spent most of 2015 building an infrastructure to expand its surgical business. With trecent acqusitions, a sales and distribution plan in place and future plans for inorganic and organic growth, Bioventus executives now say that the company is positioning itself as an orthobiologics leader.
EOS imaging partnered with Spinologics to co-develop biomechanical spine surgery simulation tools for integration with EOS imaging's cloud-based, 3D planning software.
MiMedx completed its acquisition of Stability Biologics, provider of human tissue products serving the surgical, spine and orthopaedic sectors. Stability Biologics will operate as a wholly-owned subsidiary of MiMedx.
MiMedx signed a definitive agreement to acquire Stability Biologics for US $10MM in cash and stock. Stability Biologics provides human tissue products for the surgical, spine and orthopaedic industries. The transaction is expected to close in early 1Q16.
Smith+Nephew completed its acquisition of Blue Belt Technologies, developer of the Navio surgical robotics-assistance system for unicondylar knee replacement.
NuVasive entered into a definitive agreement to acquire Ellipse Technologies for US $380MM in cash, with a potential $30MM milestone payable in 2017. The transaction is slated to close in mid-1Q16. Ellipse posted 2015 revenue of ~$40MM, +54% vs. 2014.
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