SurGenTec Gains FDA Clearance for OsteoFlo NanoPutty
OsteoFlo NanoPutty bone graft features the world's first quadphasic synthetic bone graft particles with nano-surface technology.
Empowering Orthopaedic Executives through Strategic Intelligence
Synthetic Bone Graft
Xtant Medical Launches Matriform Si for Spinal Fusion
The company announced the U.S. commercial launch of the Matriform Si, a silicated synthetic bone graft substitute designed and cleared for spinal fusion.
GreenBone Introduces Novel Wood-Based Bone Regeneration Solution
GreenBone Ortho uses technology that mimics nature to create a long-term solution using rattan, a type of wood, as the base material.
Biocomposites Signs New Exclusive Distributor in Australia
LifeHealthcare will sell STIMULAN and genex calcium matrices for surgical use in musculoskeletal infections, trauma, spine and foot/ankle.
Bioventus Gains FDA Clearance of SIGNAFUSE Bone Graft Strip
Bioventus received FDA 510(k) clearance to market SIGNAFUSE® Bioactive Bone Graft in a strip format. The strips consist of 55% bioglass by weight and have been shown to induce higher levels of osteoblast differentiation compared to other synthetic bone graft strips....
Biocomposites STIMULAN Products Added to NHS Supply Chain
STIMULAN is the first calcium matrix to receive European approval as an antibiotic carrier for use in bone and soft tissue.
SIRAKOSS Receives FDA Clearance for Osteo3 ZP Putty
Osteo3 ZP Putty combines best-in-class bone repair with intraoperative ease-of-use for spine and trauma bone grafting applications.
BONESUPPORT Launches Direct Sales in the Netherlands
BONESUPPORT's bone graft substitutes are based on the patented CERAMENT technology platform. Direct sales commence in July 2020.
Biocomposites Granted CE Mark for STIMULAN
This represents the first calcium matrix to receive European approval as an antibiotic carrier for use in bone and soft tissue.
BONESUPPORT Announces CERAMENT Preclinical Long-term Study Results
New preclinical data confirms that local delivery of a bisphosphonate in combination with CERAMENT can regenerate cancellous bone.
BBS-Bioactive Bone Substitutes Granted U.S. Patent
BBS-Bioactive Bone Substitutes' patent application protecting ARTEBONE® bone graft substitute has been accepted in the U.S.
BONESUPPORT to Submit a De Novo Application for CERAMENT G
BONESUPPORT will submit a De Novo application for approval of CERAMENT® G in the treatment of osteomyelitis.
Kuros Strengthens Orthobiologics Patent Portfolio
Kuros Biosurgery was granted U.S. patents related to the MagnetOs product line and parathyroid hormones containing matrices for spinal fusion.
Renovos to Develop Next-Gen Technology to “Tame” BMP-2 Diffusion
Regenerative medicine is an emerging market with solutions to not only heal but also grow tissue and bone. Renovos is addressing the issue of biological molecule diffusion through a synthetic nanoclay gel technology platform called Renovite.
Acumed Signs Distribution Agreement with Vivorte
Acumed entered into an agreement to distribute Vivorte's orthobiologic portfolio on an exclusive basis.
Biogennix Gains Additional FDA Clearance for Agilon Moldable Bone Graft
Biogennix received FDA 510(k) clearance to market Agilon™ moldable bone graft for use in posterolateral spine procedures when mixed with autograft.
Biocomposites Launches STIMULAN Rapid Cure 3cc
Biocomposites commenced U.S. launch of STIMULAN® Rapid Cure 3cc synthetic calcium sulfate, designed specifically for smaller voids in the foot and ankle.
Bone Solutions Surpasses 1,000 Cases with OsteoCrete Bone Void Filler
Bone Solutions announced successful implantation in over 1,000 cases with magnesium-based OsteoCrete® bone void filler.
Graftys and OrthoPediatrics Partner on U.S. Distribution of Bone Cement
Graftys entered into a distribution agreement whereby OrthoPediatrics will market Graftys® QuickSet in the U.S.
Onkos Surgical Launches GenVie Magnesium Bone Scaffold
Onkos Surgical is marketing GenVie™ magnesium-based bone void filler through a distribution agreement with Bone Solutions.
GreenBone Gains CE Mark Approval for Bone Substitute
GreenBone Ortho received approval under the CE Mark for GreenBone Bone Substitute™.
Biologics4Life Secures License to Bone Tissue Regeneration Technology
Biologics4Life completed an exclusive licensing agreement to secure rights to initial technologies for bone tissue regeneration.
OrthoPediatrics Launches QuickPack Bone Graft Substitute
OrthoPediatrics commenced U.S. launch of QuickPack™ synthetic bone graft substitute.
Anika Fully Launches TACTOSET in the U.S.
Anika Therapeutics is commencing full U.S. commercial launch of TACTOSET surgically-delivered therapy for bone repair procedures.
Biomatlante Acquired by Advanced Medical Solutions
Advanced Medical Solutions acquired Biomatlante, developer, and manufacturer of orthobiologic products with application in joint reconstruction, spine, trauma, and sports medicine procedures.
In2Bones Introduces CoLink Bone Graft Harvester and Tribio Backfill Plugs
In2Bones commenced U.S. launch of the CoLink® Bone Graft Harvester and Tribio™ Backfill Plug System.
U.S. Spinal Hardware Sales Continues to Drive NuVasive Growth
ARTEBONE Patent Application Accepted in Canada
BBS-Bioactive Bone Substitutes' patent application regarding a bone protein preparation has been accepted in Canada.
ADAM Project to Launch Clinical Trials of 3D-Printed Synthetic Bone
ADAM, a 3D bone printing project, plans to complete pre-clinical trials within the month and commence first human trials by the end of 2019.
curasan Gains CE Mark for Spinevisc Hyaluronic Acid
curasan is launching Spinevisc® hyaluronic acid for the treatment of facet syndrome.
NanoFUSE Launches NanoSTRIP 100% Bioactive Glass Synthetic Biologic
NanoFUSE commenced market release of NanoSTRIP, a 100% bioactive glass synthetic biologic strip indicated for spine and orthopedic use.
Kuros Biosciences Signs Distribution Agreement with Surgical Specialties for MagnetOs
Kuros Biosciences entered into an agreement whereby Surgical Specialties will distribute MagnetOs synthetic bone graft in Australia and New Zealand.
BONESUPPORT is the Exclusive U.S. Distributor of CERAMENT
BONESUPPORT is now the exclusive distributor of CERAMENT® bone void filler in the U.S.
Exactech Announces First Surgeries Using InterSep Bone Void Filler
Exactech announced the successful first procedure using InterSep calcium sulfate bone void filler.
Collagen Matrix Gains FDA Clearance for Bioactive Moldable Bone Graft Matrix
Collagen Matrix received FDA 510(k) clearance to market OssiMend® Bioactive Moldable Bone Graft Matrix.
FzioMed Enrolls 50th Patient in Oxiplex Study
FzioMed reached a milestone of 1/3 patient enrollment in a clinical study of Oxiplex® gel for reduction of pain following partial discectomy.
Graftys Completes Capital Raise for Expansion
Graftys completed a ‚¬4.1MM (~US $4.6MM) funding round. Proceeds will support commercialization of QuickSet cement and HBS injectable calcium phosphate bone graft substitute.
Atreon Orthopedics Receives FDA Clearance for Rotator Cuff Regeneration Device
Atreon Orthopedics received FDA 510(k) clearance to market the Rotium Bioresorbable Wick for the treatment of rotator cuff injuries.
Bone Solutions Surpasses 500 Cases with OsteoCrete Bone Void Filler
Bone Solutions announced successful implantation in over 500 cases with magnesium-based OsteoCrete® bone void filler.
AxioMed and NanoFUSE Biologics to be Available for Acquisition
KICVentures seeks funding to prepare its portfolio companies, AxioMed and NanoFUSE Biologics, to be acquisition targets.
SIRAKOSS Osteo3 Gains CE Mark
SIRAKOSS received approval under the CE Mark for Osteo3 nanosynthetic bone graft substitute.
Bioventus Launches OSTEOMATRIX+ Biphasic Bone Graft
Bioventus introduced OSTEOMATRIX+® biphasic bone graft for orthopaedic and spine applications.
Kuros Gains FDA Clearance for Expanded MagnetOs Putty Indications
Kuros Biosciences was granted FDA 510(k) clearance to market MagnetOs Putty as a standalone bone graft in the extremities and pelvis.
Innovasis Signs Private-Label Agreement with Stability Biologics
Innovasis entered into a private-label agreement with Stability Biologics that includes access to Physio® bone allograft. Product launch is expected by year-end.
BONESUPPORT Begins Direct U.S. Sales of CERAMENT Bone Void Filler
BONESUPPORT commenced direct U.S. sales of bone void filler CERAMENT® BVF.
Kuros Biosciences: First Procedure in MagnetOS Spinal Fusion Trial
The first patient has been treated in a multicenter study comparing Kuros Bioscience's MagnetOs bone graft substitute vs. autologous bone in spinal fusion.
Synergy Biomedical Launches BIOSPHERE MIS PUTTY
Synergy Biomedical received FDA 510(k) clearance and commenced full launch of BIOSPHERE® MIS PUTTY for open, mini-open and percutaneous minimally invasive procedures.
Baxter Gains FDA Clearance for Bone Graft Substitute
Baxter International received FDA 510(k) clearance for its Actifuse Flow bone graft substitute.
BONESUPPORT’s CERAMENT G Approved by Health Canada
BONESUPPORT received regulatory approval from Health Canada for CERAMENT® G gentamicin-eluting injectable ceramic bone graft substitute.
BONESUPPORT Signs Strategic Agreement with MTF Biologics
BONESUPPORT entered into an agreement with MTF Biologics, gaining U.S. rights to distribute two demineralized bone matrices.
NuVasive Launches AttraX Scaffold Biologic in the US
NuVasive commenced U.S. launch of AttraX® Scaffold ceramic-collagen bone graft.
DePuy Synthes, Prosidyan Partner on FIBERGRAFT Products
DePuy Synthes entered into an exclusive agreement to promote Prosidyan's FIBERGRAFT® synthetic bone graft in spinal fusion, starting in 2Q18.
Kuros Biosciences Receives CE Mark Approval for MagnetOs Putty
Kuros Biosciences received CE Mark approval for MagnetOs Putty bone void filler.
Cerapedics Launching IDE Study of P-15L Bone Graft in TLIF
Cerapedics received FDA approval for an IDE clinical trial of P-15L Peptide Enhanced Bone Graft vs. autograft in TLIF to treat degenerative disc disease.
Ortho RTi Receives Notice of Allowance for European Patent
Ortho Regenerative Technologies received an EU Notice of Allowance for a patent that will protect the composition of Ortho-R biopolymer for soft tissue repair.
Synergy Biomedical Launching BIOSPHERE PUTTY in Australia
Synergy Biomedical received Therapeutic Goods Administration clearance and commenced launch of BIOSPHERE PUTTY bioactive bone graft in Australia.
Biomatlante’s MBCP Matrix Selected for Fracture Study
Biomatlante's MBCP+ synthetic bone graft matrix has been selected for comparison to autograft in a 5-year trial in the treatment of long bone nonunions.
Leader Biomedical Acquires International Orthopaedics
Leader Biomedical is acquiring International Orthopaedics, manufacturer of ICON total hip and hip resurfacing implants and instruments.
Bioventus and LifeLink Collaborate on Bone Allograft
Bioventus and LifeLink Tissue Bank will co-develop bone allograft for spine and trauma applications.
Bone Solutions Reaches 50 Implants of OsteoCrete Bone Void Filler
Bone Solutions reached the milestone of 50 successful implants of OsteoCrete® magnesium-based bone void filler.
ReBOSSIS Bone Scaffold Gains FDA Clearance in Spine
ORTHOReBIRTH USA received FDA 510(k) clearance to market ReBOSSIS® biosynthetic bone scaffold for use in posterolateral spine procedures.
Anika Gains FDA Clearance for HA-based Bone Void Filler
Anika Therapeutics received FDA 510(k) clearance to market a resorbable, injectable hyaluronic acid-based bone void filler.
Bone Biologics Study: Preclinical Data for Spine Fusion Demonstrates Osteopromotive Properties
Preclinical study results indicate that Bone Biologics' rhNELL-1 growth factor effectively promoted bone formation in a spine model.
Xtant Medical and curasan Enter Distribution Agreement
Xtant Medical entered the U.S. bone graft substitute market through a distribution agreement with curasan.
Prosidyan Launches FIBERGRAFT BG MATRIX for Posterolateral Spinal Fusion
Prosidyan announced FDA 510(k) clearance and commercial launch of FIBERGRAFT BG Matrix, a bone graft substitute for posterolateral spinal fusion.
Artoss Launching NanoBone QD Bone Graft
Artoss introduced NanoBone® QD bone graft, comprising NanoBone SBX putty in an application designed for quick delivery.
Vivorte Launches New Bone Graft Products
Vivorté launched FORTERA™ and REGENTO™ bone graft products for orthopaedic surgery.
Bone Solutions Launches OsteoCrete Magnesium-Based Bone Void Filler
Bone Solutions commenced U.S. launch of OsteoCrete®, the first magnesium-based bone void filler in the U.S.
Kuros Biosciences Receives Additional FDA 510(k) Clearance for MagnetOs Putty
Kuros Biosciences received FDA 510(k) clearance to market MagnetOs synthetic bone graft putty as an autograft extender in the posterolateral spine.
Tissue Regenix Proposes Acquisition of CellRight Technologies
Tissue Regenix proposes to acquire CellRight Technologies for US $30MM, to offer products for bone and soft tissue regeneration.
ChoiceSpine Launches Biologics Portfolio
ChoiceSpine launched a biologics portfolio, adding allograft, synthetic bone graft and amnion offerings to complement its spinal hardware portfolio.
Premier to Offer Bioventus Surgical Orthobiologics Products to Members
Premier is now offering Bioventus' full surgical orthobiologics product portfolio to its U.S. membership, comprising 3,750 hospitals and >130,000 provider organizations.
SurGenTec Receives US Patent for GRAFTGUN
SurGenTec was granted U.S. Patent No. 9,655,748, Bone Graft Delivery System and Method for Using Same, pertaining to the GRAFTGUN® device.
NovaBone Adds New Biologically-active Bone Graft Substitutes
NovaBone Products launched NovaBone IRM and NovaBone IRM MacroPOR to its portfolio of biologically-active bone graft substitutes.
BONESUPPORT Enrolls First Patient in FORTIFY Trial With CERAMENT G
BONESUPPORT enrolled the first patient in the pivotal IDE trial of CERAMENT G in the surgical repair of open diaphyseal tibial fractures.
Amend Surgical Enters Agreement with UFRF for Biomimetic Bone Development
Amend Surgical entered into an exclusive agreement with The University of Florida Research Foundation to license patents for the development of Biomimetic Bone.
BONESUPPORT Extends U.S. Distribution Agreement with Zimmer Biomet for CERAMENT
BONESUPPORT extended its U.S. distribution agreement with Zimmer Biomet (ZBH), continuing ZBH's exclusive rights for CERAMENT BONE VOID FILLER.
Positive Interim Data from Trial for BonyPid Antibiotic Eluting Bone Substitute
Interim results from study of BonyPid®-1000 bone substitute in the treatment of open tibial fractures indicate that the product met performance and safety endpoints in first patients at 6 months.
Bioactive Glass Shown Effective Towards Antibiotic-resistant Bacteria
Studies of BonAlive® indicate that the naturally-antibacterial bioactive glass yields excellent results in the treatment of osteomyelitis, without the use of local antibiotics.
Synergy Biomedical Receives CE Mark for Biosphere Putty
Synergy Biomedical received approval under the CE Mark for BIOSPHERE synthetic bone graft putty.
Sirakoss Receives US Patents for Bone Graft Technologies
SIRAKOSS was granted two U.S. patents covering synthetic bone graft technologies, and seeks to raise £3.5MM to £5.0MM in support of U.S. and EU regulatory approvals.
Zimmer Biomet Launches PrimaGen Advanced Allograft
Zimmer Biomet launched PrimaGen Advanced™ Allograft, an autograft substitute comprising cancellous bone + demineralized cortical bone fibers with verified osteoinductivity.
Study Results: Biomatlante’s MBCP+ Synthetic Bone Graft and MSCs
Study results demonstrated a high rate of clinical success from a combination of Biomatlante's MBCP+™ synthetic bone graft plus mesenchymal stem cells, particularly in the treatment of long bone non-union fractures.
curasan Receives FDA Clearance for CERASORB Ortho FOAM
curasan received FDA 510(k) clearance to market CERASORB Ortho FOAM synthetic bone material for the treatment of bone defects in the extremities and pelvis.
Artoss Receives FDA Clearance to Market NanoBone SBX Putty
Artoss announced FDA 510(k) clearance to market NanoBone® SBX Putty.
BONESUPPORT Raises $37MM to Support Cerament
BONESUPPORT raised SEK 327MM (~US $37MM). Funds will support clinical data collection, product pipeline development and expansion of CERAMENT sales in existing and new markets.
RTI Surgical Receives Regulatory Clearances for nanOss Bioactive in Australia, Europe
RTI Surgical received regulatory clearance for nanOss® Bioactive bone void filler in Australia, as well as CE Mark for nanOss Bioactive Loaded and nanOss Bioactive 3D in Europe.
BONESUPPORT Receives FDA Approval to Initiate IDE Clinical Study
BONESUPPORT received FDA approval to launch an Investigational Device Exemption study of CERAMENT G bone graft substitute in the treament of open diaphyseal tibial fractures.
Bone Biologics Signs Option to License Nell-1 Bone Growth Factor for Use in Osteoporosis
Bone Biologics signed an option agreement with UCLA for an opportunity to exclusively license the use of Nell-1 bone growth factor in the treatment of osteoporosis.
Pre-Clinical Study Highlights CERAMENT’s Bone Remodeling Properties
Pre-clinical study results demonstrated that BONESUPPORT's CERAMENT™, loaded with rhBMP-2 + zoledronic acid in very low doses, was able to quantitatively/qualitatively generate a high amount of mineralized bone volume.
NuVasive Announces U.S. Launch of AttraX® Putty
NuVasive announced the U.S. launch of AttraX® Putty, a synthetic bone graft for use in the posterior lateral spine.
Tecres and Keensight to Form Demetra
Demetra Holding has formed with investment from Tecres and Keensight, which acquired aap Implantate's biomaterials assets.
Orthocell Gains approval for Collagen Scaffold Study
Orthocell was granted ethical approval in Australia for a clinical study of a microfracture technique using the Celgro SMRT Graft collagen scaffold.
New Product Launches from NuVasive
NuVasive announced launch of new products such as AttraX® Putty Biotextured™ bone graft, the Reline® Modular system, next-gen MAS® TLIF 2 technology, etc.
Bone Solutions Signs Distribution Agreement with Next Health
Bone Solutions signed an exclusive 10-state U.S. distribution agreement with Next Health for OsteoCrete magnesium-based bone graft substitute.
BONESUPPORT Launches CERAMENT|G 5 mL in the EU
BONESUPPORT launched a 5mL version of CERAMENT™|G antibiotic-eluting bone substitute in the EU to support small joint and extremity indications.
BONESUPPORT Expands CERAMENT Procedure Registry
BONESUPPORT expanded its 2014 injectable bone substitute registry to include 230 CERAMENT™ G procedures, as well as procedures involving the CERAMENT V formulation.
20,000 Patients Treated with BONESUPPORT’s CERAMENT
BONESUPPORT announced the milestone of >20,000 patients treated worldwide to date with CERAMENT™ injectable drug-eluting bone substitute products.
Vivex Biomedical Raised $6.6MM in Series A Funding
Vivex Biomedical raised US $6.6MM of a potential $10MM offering of Series A Convertible Preferred Stock.
Xtant Medical Launches Matriform Si for Spinal Fusion
The company announced the U.S. commercial launch of the Matriform Si, a silicated synthetic bone graft substitute designed and cleared for spinal fusion.
GreenBone Introduces Novel Wood-Based Bone Regeneration Solution
GreenBone Ortho uses technology that mimics nature to create a long-term solution using rattan, a type of wood, as the base material.
Biocomposites Signs New Exclusive Distributor in Australia
LifeHealthcare will sell STIMULAN and genex calcium matrices for surgical use in musculoskeletal infections, trauma, spine and foot/ankle.
Bioventus Gains FDA Clearance of SIGNAFUSE Bone Graft Strip
Bioventus received FDA 510(k) clearance to market SIGNAFUSE® Bioactive Bone Graft in a strip format. The strips consist of 55% bioglass by weight and have been shown to induce higher levels of osteoblast differentiation compared to other synthetic bone graft strips....
Biocomposites STIMULAN Products Added to NHS Supply Chain
STIMULAN is the first calcium matrix to receive European approval as an antibiotic carrier for use in bone and soft tissue.
SIRAKOSS Receives FDA Clearance for Osteo3 ZP Putty
Osteo3 ZP Putty combines best-in-class bone repair with intraoperative ease-of-use for spine and trauma bone grafting applications.
BONESUPPORT Launches Direct Sales in the Netherlands
BONESUPPORT's bone graft substitutes are based on the patented CERAMENT technology platform. Direct sales commence in July 2020.
Biocomposites Granted CE Mark for STIMULAN
This represents the first calcium matrix to receive European approval as an antibiotic carrier for use in bone and soft tissue.
BONESUPPORT Announces CERAMENT Preclinical Long-term Study Results
New preclinical data confirms that local delivery of a bisphosphonate in combination with CERAMENT can regenerate cancellous bone.
BBS-Bioactive Bone Substitutes Granted U.S. Patent
BBS-Bioactive Bone Substitutes' patent application protecting ARTEBONE® bone graft substitute has been accepted in the U.S.
BONESUPPORT to Submit a De Novo Application for CERAMENT G
BONESUPPORT will submit a De Novo application for approval of CERAMENT® G in the treatment of osteomyelitis.
Kuros Strengthens Orthobiologics Patent Portfolio
Kuros Biosurgery was granted U.S. patents related to the MagnetOs product line and parathyroid hormones containing matrices for spinal fusion.
Renovos to Develop Next-Gen Technology to “Tame” BMP-2 Diffusion
Regenerative medicine is an emerging market with solutions to not only heal but also grow tissue and bone. Renovos is addressing the issue of biological molecule diffusion through a synthetic nanoclay gel technology platform called Renovite.
Acumed Signs Distribution Agreement with Vivorte
Acumed entered into an agreement to distribute Vivorte's orthobiologic portfolio on an exclusive basis.
Biogennix Gains Additional FDA Clearance for Agilon Moldable Bone Graft
Biogennix received FDA 510(k) clearance to market Agilon™ moldable bone graft for use in posterolateral spine procedures when mixed with autograft.
Biocomposites Launches STIMULAN Rapid Cure 3cc
Biocomposites commenced U.S. launch of STIMULAN® Rapid Cure 3cc synthetic calcium sulfate, designed specifically for smaller voids in the foot and ankle.
Bone Solutions Surpasses 1,000 Cases with OsteoCrete Bone Void Filler
Bone Solutions announced successful implantation in over 1,000 cases with magnesium-based OsteoCrete® bone void filler.
Graftys and OrthoPediatrics Partner on U.S. Distribution of Bone Cement
Graftys entered into a distribution agreement whereby OrthoPediatrics will market Graftys® QuickSet in the U.S.
Onkos Surgical Launches GenVie Magnesium Bone Scaffold
Onkos Surgical is marketing GenVie™ magnesium-based bone void filler through a distribution agreement with Bone Solutions.
GreenBone Gains CE Mark Approval for Bone Substitute
GreenBone Ortho received approval under the CE Mark for GreenBone Bone Substitute™.
Biologics4Life Secures License to Bone Tissue Regeneration Technology
Biologics4Life completed an exclusive licensing agreement to secure rights to initial technologies for bone tissue regeneration.
OrthoPediatrics Launches QuickPack Bone Graft Substitute
OrthoPediatrics commenced U.S. launch of QuickPack™ synthetic bone graft substitute.
Anika Fully Launches TACTOSET in the U.S.
Anika Therapeutics is commencing full U.S. commercial launch of TACTOSET surgically-delivered therapy for bone repair procedures.
Biomatlante Acquired by Advanced Medical Solutions
Advanced Medical Solutions acquired Biomatlante, developer, and manufacturer of orthobiologic products with application in joint reconstruction, spine, trauma, and sports medicine procedures.
In2Bones Introduces CoLink Bone Graft Harvester and Tribio Backfill Plugs
In2Bones commenced U.S. launch of the CoLink® Bone Graft Harvester and Tribio™ Backfill Plug System.
U.S. Spinal Hardware Sales Continues to Drive NuVasive Growth
ARTEBONE Patent Application Accepted in Canada
BBS-Bioactive Bone Substitutes' patent application regarding a bone protein preparation has been accepted in Canada.
ADAM Project to Launch Clinical Trials of 3D-Printed Synthetic Bone
ADAM, a 3D bone printing project, plans to complete pre-clinical trials within the month and commence first human trials by the end of 2019.
curasan Gains CE Mark for Spinevisc Hyaluronic Acid
curasan is launching Spinevisc® hyaluronic acid for the treatment of facet syndrome.
NanoFUSE Launches NanoSTRIP 100% Bioactive Glass Synthetic Biologic
NanoFUSE commenced market release of NanoSTRIP, a 100% bioactive glass synthetic biologic strip indicated for spine and orthopedic use.
Kuros Biosciences Signs Distribution Agreement with Surgical Specialties for MagnetOs
Kuros Biosciences entered into an agreement whereby Surgical Specialties will distribute MagnetOs synthetic bone graft in Australia and New Zealand.
BONESUPPORT is the Exclusive U.S. Distributor of CERAMENT
BONESUPPORT is now the exclusive distributor of CERAMENT® bone void filler in the U.S.
Exactech Announces First Surgeries Using InterSep Bone Void Filler
Exactech announced the successful first procedure using InterSep calcium sulfate bone void filler.
Collagen Matrix Gains FDA Clearance for Bioactive Moldable Bone Graft Matrix
Collagen Matrix received FDA 510(k) clearance to market OssiMend® Bioactive Moldable Bone Graft Matrix.
FzioMed Enrolls 50th Patient in Oxiplex Study
FzioMed reached a milestone of 1/3 patient enrollment in a clinical study of Oxiplex® gel for reduction of pain following partial discectomy.
Graftys Completes Capital Raise for Expansion
Graftys completed a ‚¬4.1MM (~US $4.6MM) funding round. Proceeds will support commercialization of QuickSet cement and HBS injectable calcium phosphate bone graft substitute.
Atreon Orthopedics Receives FDA Clearance for Rotator Cuff Regeneration Device
Atreon Orthopedics received FDA 510(k) clearance to market the Rotium Bioresorbable Wick for the treatment of rotator cuff injuries.
Bone Solutions Surpasses 500 Cases with OsteoCrete Bone Void Filler
Bone Solutions announced successful implantation in over 500 cases with magnesium-based OsteoCrete® bone void filler.
AxioMed and NanoFUSE Biologics to be Available for Acquisition
KICVentures seeks funding to prepare its portfolio companies, AxioMed and NanoFUSE Biologics, to be acquisition targets.
SIRAKOSS Osteo3 Gains CE Mark
SIRAKOSS received approval under the CE Mark for Osteo3 nanosynthetic bone graft substitute.
Bioventus Launches OSTEOMATRIX+ Biphasic Bone Graft
Bioventus introduced OSTEOMATRIX+® biphasic bone graft for orthopaedic and spine applications.
Kuros Gains FDA Clearance for Expanded MagnetOs Putty Indications
Kuros Biosciences was granted FDA 510(k) clearance to market MagnetOs Putty as a standalone bone graft in the extremities and pelvis.
Innovasis Signs Private-Label Agreement with Stability Biologics
Innovasis entered into a private-label agreement with Stability Biologics that includes access to Physio® bone allograft. Product launch is expected by year-end.
BONESUPPORT Begins Direct U.S. Sales of CERAMENT Bone Void Filler
BONESUPPORT commenced direct U.S. sales of bone void filler CERAMENT® BVF.
Kuros Biosciences: First Procedure in MagnetOS Spinal Fusion Trial
The first patient has been treated in a multicenter study comparing Kuros Bioscience's MagnetOs bone graft substitute vs. autologous bone in spinal fusion.
Synergy Biomedical Launches BIOSPHERE MIS PUTTY
Synergy Biomedical received FDA 510(k) clearance and commenced full launch of BIOSPHERE® MIS PUTTY for open, mini-open and percutaneous minimally invasive procedures.
Baxter Gains FDA Clearance for Bone Graft Substitute
Baxter International received FDA 510(k) clearance for its Actifuse Flow bone graft substitute.
BONESUPPORT’s CERAMENT G Approved by Health Canada
BONESUPPORT received regulatory approval from Health Canada for CERAMENT® G gentamicin-eluting injectable ceramic bone graft substitute.
BONESUPPORT Signs Strategic Agreement with MTF Biologics
BONESUPPORT entered into an agreement with MTF Biologics, gaining U.S. rights to distribute two demineralized bone matrices.
NuVasive Launches AttraX Scaffold Biologic in the US
NuVasive commenced U.S. launch of AttraX® Scaffold ceramic-collagen bone graft.
DePuy Synthes, Prosidyan Partner on FIBERGRAFT Products
DePuy Synthes entered into an exclusive agreement to promote Prosidyan's FIBERGRAFT® synthetic bone graft in spinal fusion, starting in 2Q18.
Kuros Biosciences Receives CE Mark Approval for MagnetOs Putty
Kuros Biosciences received CE Mark approval for MagnetOs Putty bone void filler.
Cerapedics Launching IDE Study of P-15L Bone Graft in TLIF
Cerapedics received FDA approval for an IDE clinical trial of P-15L Peptide Enhanced Bone Graft vs. autograft in TLIF to treat degenerative disc disease.
Ortho RTi Receives Notice of Allowance for European Patent
Ortho Regenerative Technologies received an EU Notice of Allowance for a patent that will protect the composition of Ortho-R biopolymer for soft tissue repair.
Synergy Biomedical Launching BIOSPHERE PUTTY in Australia
Synergy Biomedical received Therapeutic Goods Administration clearance and commenced launch of BIOSPHERE PUTTY bioactive bone graft in Australia.
Biomatlante’s MBCP Matrix Selected for Fracture Study
Biomatlante's MBCP+ synthetic bone graft matrix has been selected for comparison to autograft in a 5-year trial in the treatment of long bone nonunions.
Leader Biomedical Acquires International Orthopaedics
Leader Biomedical is acquiring International Orthopaedics, manufacturer of ICON total hip and hip resurfacing implants and instruments.
Bioventus and LifeLink Collaborate on Bone Allograft
Bioventus and LifeLink Tissue Bank will co-develop bone allograft for spine and trauma applications.
Bone Solutions Reaches 50 Implants of OsteoCrete Bone Void Filler
Bone Solutions reached the milestone of 50 successful implants of OsteoCrete® magnesium-based bone void filler.
ReBOSSIS Bone Scaffold Gains FDA Clearance in Spine
ORTHOReBIRTH USA received FDA 510(k) clearance to market ReBOSSIS® biosynthetic bone scaffold for use in posterolateral spine procedures.
Anika Gains FDA Clearance for HA-based Bone Void Filler
Anika Therapeutics received FDA 510(k) clearance to market a resorbable, injectable hyaluronic acid-based bone void filler.
Bone Biologics Study: Preclinical Data for Spine Fusion Demonstrates Osteopromotive Properties
Preclinical study results indicate that Bone Biologics' rhNELL-1 growth factor effectively promoted bone formation in a spine model.
Xtant Medical and curasan Enter Distribution Agreement
Xtant Medical entered the U.S. bone graft substitute market through a distribution agreement with curasan.
Prosidyan Launches FIBERGRAFT BG MATRIX for Posterolateral Spinal Fusion
Prosidyan announced FDA 510(k) clearance and commercial launch of FIBERGRAFT BG Matrix, a bone graft substitute for posterolateral spinal fusion.
Artoss Launching NanoBone QD Bone Graft
Artoss introduced NanoBone® QD bone graft, comprising NanoBone SBX putty in an application designed for quick delivery.
Vivorte Launches New Bone Graft Products
Vivorté launched FORTERA™ and REGENTO™ bone graft products for orthopaedic surgery.
Bone Solutions Launches OsteoCrete Magnesium-Based Bone Void Filler
Bone Solutions commenced U.S. launch of OsteoCrete®, the first magnesium-based bone void filler in the U.S.
Kuros Biosciences Receives Additional FDA 510(k) Clearance for MagnetOs Putty
Kuros Biosciences received FDA 510(k) clearance to market MagnetOs synthetic bone graft putty as an autograft extender in the posterolateral spine.
Tissue Regenix Proposes Acquisition of CellRight Technologies
Tissue Regenix proposes to acquire CellRight Technologies for US $30MM, to offer products for bone and soft tissue regeneration.
ChoiceSpine Launches Biologics Portfolio
ChoiceSpine launched a biologics portfolio, adding allograft, synthetic bone graft and amnion offerings to complement its spinal hardware portfolio.
Premier to Offer Bioventus Surgical Orthobiologics Products to Members
Premier is now offering Bioventus' full surgical orthobiologics product portfolio to its U.S. membership, comprising 3,750 hospitals and >130,000 provider organizations.
SurGenTec Receives US Patent for GRAFTGUN
SurGenTec was granted U.S. Patent No. 9,655,748, Bone Graft Delivery System and Method for Using Same, pertaining to the GRAFTGUN® device.
NovaBone Adds New Biologically-active Bone Graft Substitutes
NovaBone Products launched NovaBone IRM and NovaBone IRM MacroPOR to its portfolio of biologically-active bone graft substitutes.
BONESUPPORT Enrolls First Patient in FORTIFY Trial With CERAMENT G
BONESUPPORT enrolled the first patient in the pivotal IDE trial of CERAMENT G in the surgical repair of open diaphyseal tibial fractures.
Amend Surgical Enters Agreement with UFRF for Biomimetic Bone Development
Amend Surgical entered into an exclusive agreement with The University of Florida Research Foundation to license patents for the development of Biomimetic Bone.
BONESUPPORT Extends U.S. Distribution Agreement with Zimmer Biomet for CERAMENT
BONESUPPORT extended its U.S. distribution agreement with Zimmer Biomet (ZBH), continuing ZBH's exclusive rights for CERAMENT BONE VOID FILLER.
Positive Interim Data from Trial for BonyPid Antibiotic Eluting Bone Substitute
Interim results from study of BonyPid®-1000 bone substitute in the treatment of open tibial fractures indicate that the product met performance and safety endpoints in first patients at 6 months.
Bioactive Glass Shown Effective Towards Antibiotic-resistant Bacteria
Studies of BonAlive® indicate that the naturally-antibacterial bioactive glass yields excellent results in the treatment of osteomyelitis, without the use of local antibiotics.
Synergy Biomedical Receives CE Mark for Biosphere Putty
Synergy Biomedical received approval under the CE Mark for BIOSPHERE synthetic bone graft putty.
Sirakoss Receives US Patents for Bone Graft Technologies
SIRAKOSS was granted two U.S. patents covering synthetic bone graft technologies, and seeks to raise £3.5MM to £5.0MM in support of U.S. and EU regulatory approvals.
Zimmer Biomet Launches PrimaGen Advanced Allograft
Zimmer Biomet launched PrimaGen Advanced™ Allograft, an autograft substitute comprising cancellous bone + demineralized cortical bone fibers with verified osteoinductivity.
Study Results: Biomatlante’s MBCP+ Synthetic Bone Graft and MSCs
Study results demonstrated a high rate of clinical success from a combination of Biomatlante's MBCP+™ synthetic bone graft plus mesenchymal stem cells, particularly in the treatment of long bone non-union fractures.
curasan Receives FDA Clearance for CERASORB Ortho FOAM
curasan received FDA 510(k) clearance to market CERASORB Ortho FOAM synthetic bone material for the treatment of bone defects in the extremities and pelvis.
Artoss Receives FDA Clearance to Market NanoBone SBX Putty
Artoss announced FDA 510(k) clearance to market NanoBone® SBX Putty.
BONESUPPORT Raises $37MM to Support Cerament
BONESUPPORT raised SEK 327MM (~US $37MM). Funds will support clinical data collection, product pipeline development and expansion of CERAMENT sales in existing and new markets.
RTI Surgical Receives Regulatory Clearances for nanOss Bioactive in Australia, Europe
RTI Surgical received regulatory clearance for nanOss® Bioactive bone void filler in Australia, as well as CE Mark for nanOss Bioactive Loaded and nanOss Bioactive 3D in Europe.
BONESUPPORT Receives FDA Approval to Initiate IDE Clinical Study
BONESUPPORT received FDA approval to launch an Investigational Device Exemption study of CERAMENT G bone graft substitute in the treament of open diaphyseal tibial fractures.
Bone Biologics Signs Option to License Nell-1 Bone Growth Factor for Use in Osteoporosis
Bone Biologics signed an option agreement with UCLA for an opportunity to exclusively license the use of Nell-1 bone growth factor in the treatment of osteoporosis.
Pre-Clinical Study Highlights CERAMENT’s Bone Remodeling Properties
Pre-clinical study results demonstrated that BONESUPPORT's CERAMENT™, loaded with rhBMP-2 + zoledronic acid in very low doses, was able to quantitatively/qualitatively generate a high amount of mineralized bone volume.
NuVasive Announces U.S. Launch of AttraX® Putty
NuVasive announced the U.S. launch of AttraX® Putty, a synthetic bone graft for use in the posterior lateral spine.
Tecres and Keensight to Form Demetra
Demetra Holding has formed with investment from Tecres and Keensight, which acquired aap Implantate's biomaterials assets.
Orthocell Gains approval for Collagen Scaffold Study
Orthocell was granted ethical approval in Australia for a clinical study of a microfracture technique using the Celgro SMRT Graft collagen scaffold.
New Product Launches from NuVasive
NuVasive announced launch of new products such as AttraX® Putty Biotextured™ bone graft, the Reline® Modular system, next-gen MAS® TLIF 2 technology, etc.
Bone Solutions Signs Distribution Agreement with Next Health
Bone Solutions signed an exclusive 10-state U.S. distribution agreement with Next Health for OsteoCrete magnesium-based bone graft substitute.
BONESUPPORT Launches CERAMENT|G 5 mL in the EU
BONESUPPORT launched a 5mL version of CERAMENT™|G antibiotic-eluting bone substitute in the EU to support small joint and extremity indications.
BONESUPPORT Expands CERAMENT Procedure Registry
BONESUPPORT expanded its 2014 injectable bone substitute registry to include 230 CERAMENT™ G procedures, as well as procedures involving the CERAMENT V formulation.
20,000 Patients Treated with BONESUPPORT’s CERAMENT
BONESUPPORT announced the milestone of >20,000 patients treated worldwide to date with CERAMENT™ injectable drug-eluting bone substitute products.
Vivex Biomedical Raised $6.6MM in Series A Funding
Vivex Biomedical raised US $6.6MM of a potential $10MM offering of Series A Convertible Preferred Stock.