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Year in Review

2011 To Date (July 2011): Merger & Acquisition Activity in Orthopaedics and Spine

2Q11

SEASPINE acquired by INTEGRA LIFESCIENCES for $89MM in cash
* Carries full range of spinal fixation products (including hardware and biologics), 2010 revenue ~$50MM
* Doubles Integra’s existing distribution network, establishes business ex-U.S.
* Integra Spine now largest component of company’s orthopaedic revenue