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Study Results: OrthoFuzIon Antimicrobial Bone Screw vs. Antibiotic-Resistant Superbugs -

Study results demonstrated that Silver Bullet Therapeutics' OrthoFuzIon® Antimicrobial Bone Screw was able to significantly disrupt the development of biofilms compared to traditional, uncoated titanium screws.

The study was designed to test the “Time Kill” and “Adherence” effectiveness of OrthoFuzIon against the top six antibiotic resistant “superbugs” as identified by the CDC, including Carbapenem-resistant Enterobacteriaceae, Klebsiella pneumoniae, Methicillin-resistant Staphylococcus aureus, ESBL-producing Enterobacteriaceae (extended-spectrum β-lactamases), Escherichia coli, Vancomycin-resistant Enterococcus, Enterococcus faecium, Multidrug-resistant Pseudomonas aeruginosa and Multidrug-resistant Acinetobacter baumannii.

OrthoFuzIon is one of the first antimicrobial implantable medical devices designed specifically for orthopaedics. The implant received CE Mark approval in early 2015 and is amassing a portfolio of patents in the U.S.

Sources: Silver Bullet Therapeutics, Inc.; ORTHOWORLD Inc.

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